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ENDOMETRIOSIS AND MALIGNANCY

ENDOMETRIOSIS AND MALIGNANCY Since the middle twenties it has been pointed out that ovarian endometriosis may undergo malignant transformation. Long and Taylor,1 in 1964, in reviewing 120 cases of primary cancer of the ovary, found several cases of primary ovarian adenocarcinoma which structurally resembled an adenocarcinoma of the endometrium. They postulated that this tumor might have its origin in benign endometriosis and, when compared to other malignant tumors, considered the prognosis relatively favorable. This report, as well as earlier communications by other authors, revived interest in malignant transformation of ovarian endometriosis. Recently, Fathalla2 surveyed 418 primary malignant ovarian tumors, and of these he was able to classify 52 with a histological appearance similar to that of malignant tumors of the uterine endometrium. In his series, the malignant endometrioid tumors accounted for approximately 12% of all primary malignant tumors of the ovary. Two specimens of adenoacanthoma and two of endometrioid carcinoma had http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

ENDOMETRIOSIS AND MALIGNANCY

JAMA , Volume 201 (4) – Jul 24, 1967

ENDOMETRIOSIS AND MALIGNANCY

Abstract


Since the middle twenties it has been pointed out that ovarian endometriosis may undergo malignant transformation. Long and Taylor,1 in 1964, in reviewing 120 cases of primary cancer of the ovary, found several cases of primary ovarian adenocarcinoma which structurally resembled an adenocarcinoma of the endometrium. They postulated that this tumor might have its origin in benign endometriosis and, when compared to other malignant tumors, considered the prognosis relatively favorable....
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Publisher
American Medical Association
Copyright
Copyright © 1967 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1967.03130040057016
Publisher site
See Article on Publisher Site

Abstract

Since the middle twenties it has been pointed out that ovarian endometriosis may undergo malignant transformation. Long and Taylor,1 in 1964, in reviewing 120 cases of primary cancer of the ovary, found several cases of primary ovarian adenocarcinoma which structurally resembled an adenocarcinoma of the endometrium. They postulated that this tumor might have its origin in benign endometriosis and, when compared to other malignant tumors, considered the prognosis relatively favorable. This report, as well as earlier communications by other authors, revived interest in malignant transformation of ovarian endometriosis. Recently, Fathalla2 surveyed 418 primary malignant ovarian tumors, and of these he was able to classify 52 with a histological appearance similar to that of malignant tumors of the uterine endometrium. In his series, the malignant endometrioid tumors accounted for approximately 12% of all primary malignant tumors of the ovary. Two specimens of adenoacanthoma and two of endometrioid carcinoma had

Journal

JAMAAmerican Medical Association

Published: Jul 24, 1967

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