Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Electroencephalographic Abnormalities in Human T-Cell Lymphotropic Virus Type I-Associated Myelopathy

Electroencephalographic Abnormalities in Human T-Cell Lymphotropic Virus Type I-Associated... Abstract • Thirty-six patients with human T-cell lymphotropic virus type I (HTLV-I)—associated myelopathy were studied by electroencephalogram. Twenty-two of 36 patients showed mild to moderate electroencephalographic abnormalities, ranging from poor organization or slowing of the background activity to theta bursts and/ or spikes. None of these abnormalities were considered specific for HTLV-I—associated myelopathy. These electroencephalographic abnormalities had no apparent relationship to duration or severity of illness, nor to HTLV-I antibody titers in the cerebrospinal fluid. We document electroencephalographic changes in HTLV-I—associated myelopathy. Our data are consistent with previous reports describing the fact that involvement of regions above the spinal cord may exist in HTLV-I—associated myelopathy. References 1. Gessain A, Barin F, Vernant JC, Gout O, Maurs L, Calender A. Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis . Lancet . 1985;2:407-410.Crossref 2. Rodgers-Johnson P, Gajdusek DC, Morgan OSC, Zaninovic V, Sarin PS, Graham DS. HTLV-I and HTLV-III antibodies and tropical spastic paraparesis . Lancet . 1985;2:1247-1248.Crossref 3. Vernant JC, Gessain A, Gout O, et al. Paraparésis spastiques tropicales en Martinique: haute prévalence d'anticorps HTLV-I . Presse Med . 1986;15:419-422. 4. Román GC. Retrovirus-associated myelopathies . Arch Neurol . 1987;44:659-663.Crossref 5. Román GC. The neuroepidemiology of tropical spastic paraparesis . Ann Neurol . 1988;23( (suppl) ):113-120.Crossref 6. Osame M, Usuku K, Izumo S, et al. HTLV-I associated myelopathy: a new clinical entity . Lancet . 1986;1:1031-1032.Crossref 7. Osame M, Matsumoto M, Usuku K, et al. Chronic progressive myelopathy associated with elevated antibodies to human T-lymphotropic virus type I and adult T-cell leukemia like cells . Ann Neurol . 1987;21:117-122.Crossref 8. Osame M, Igata A, Matsumoto M, Usuku K, Izumo S, Kosaka K. HTLV-I-associated myelopathy: a report of 85 cases . Ann Neurol . 1987;22:116. 9. Román GC, Osame M. Identity of HTLVI-associated tropical spastic paraparesis and HTLV-I-associated myelopathy . Lancet . 1988;1:651.Crossref 10. Osame M, Igata A, Matsumoto M, Usuku K, Kitajima I, Jakahashi K. On the discovery of a new clinical entity: human T-cell lymphotropic virus type I-associated myelopathy (HAM) . Shinkei Kenkyu Shinpo . 1987;31:727-745. 11. Arimura Y, Arimura K, Osame M, Igata A. Neuro-ophthalmological abnormalities in HTLVI associated myelopathy . Neuroophthalmology . 1987;7:243-248.Crossref 12. Shibasaki H, Kuroiwa Y. EEG abnormality in optic spinal form of multiple sclerosis . Eur Neurol . 1974;11:218-226.Crossref 13. Shibasaki H, Kuroiwa Y. EEG abnormality in multiple sclerosis, I: analysis based on our 30 autopsied or probable cases . Rinsho Shinkeigaku . 1973;13:477-483. 14. Hiyoshi T, Osame M, Moritoyo T, et al. Cystometric analysis of the urinary function of HTLV-I associated myelopathy: a preliminary report . Acta Med Univ Kogoshima . 1987;29( (pt 1) ):19-27. 15. Chatrian GE, Bergamini L, Dondey M, Klass DW, Lennox-Buchthal M, Petersen I. A glossary of terms most commonly used by clinical electroencephalographers . Electroencephalogr Clin Neurophysiol . 1974;37:538-548.Crossref 16. Arimura K, Rosales R, Osame M, Spencer PS, Schoenberg BS. Clinical electrophysiologic studies of HTLV-I-associated myelopathy . Arch Neurol . 1987;44:609-612.Crossref 17. Akizuki S, Nakazato O, Higuchi Y, et al. Necropsy findings in HTLV-I associated myelopathy . Lancet . 1987;1:156-157.Crossref 18. Montgomery RD, Cruickshank EK, Robertson WB, McMenemy WH. Clinical and pathological observations on Jamaican neuropathy: a report on 206 cases . Brain . 1964;87:425-462.Crossref 19. Román GC, Spencer PS, Schoenberg BS, et al. Tropical spastic paraparesis in the Seychelles Islands: a clinical and case-control neuroepidemiologic study . Neurology . 1987;37:1323-1328.Crossref 20. Robertson WB, Cruickshank EK. Jamaican (tropical) myeloneuropathy . In: Minckler J, ed. Pathology of the Nervous System . New York, NY: McGraw-Hill International Book Co; 1972;3:2466-2476. 21. Piccardo P, Ceroni M, Rodgers-Johnson P, et al. Pathological and immunological observations on tropical spastic paraparesis in patients from Jamaica . Ann Neurol . 1988;23( (suppl) ):156-160.Crossref 22. Newton M, Cruickshank K, Miller D, et al. Antibody to human T-lymphotropic virus type I in West Indian-born UK residents with spastic paraparesis . Lancet . 1987;1:415-416.Crossref 23. Bhagavati S, Ehrlich G, Kula RW, et al. Detection of human T-cell lymphoma/leukemia virus type I DNA and antigen in spinal fluid and blood of patients with chronic progressive myelopathy . N Engl J Med . 1988;318:1141-1147.Crossref 24. Furukawa Y, Une F, Osame M. Magnetic resonance imaging in HTLV-I-associated myelopathy. Rinsho Shinkei. In press. 25. Román GC, Schoenberg BS, Spencer PS, et al. Tropical spastic paraparesis (TSP) in the Seychelles Islands of the Indian Ocean: clinical, neurophysiologic, and pathologic features . Neurology . 1986;36( (suppl 1) ):106. Abstract.Crossref 26. Barkhause PE, Morgan O. Jamaican neuropathy: an electrophysiological study . Muscle Nerve . 1988;11:380-385.Crossref 27. Ludolph AC, Hugon J, Román GC, et al. A clinical neurophysiologic study of tropical spastic paraparesis . Muscle Nerve . 1988;11:392-397.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Electroencephalographic Abnormalities in Human T-Cell Lymphotropic Virus Type I-Associated Myelopathy

Loading next page...
 
/lp/american-medical-association/electroencephalographic-abnormalities-in-human-t-cell-lymphotropic-eFFhnhtegV
Publisher
American Medical Association
Copyright
Copyright © 1989 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1989.00520410047022
Publisher site
See Article on Publisher Site

Abstract

Abstract • Thirty-six patients with human T-cell lymphotropic virus type I (HTLV-I)—associated myelopathy were studied by electroencephalogram. Twenty-two of 36 patients showed mild to moderate electroencephalographic abnormalities, ranging from poor organization or slowing of the background activity to theta bursts and/ or spikes. None of these abnormalities were considered specific for HTLV-I—associated myelopathy. These electroencephalographic abnormalities had no apparent relationship to duration or severity of illness, nor to HTLV-I antibody titers in the cerebrospinal fluid. We document electroencephalographic changes in HTLV-I—associated myelopathy. Our data are consistent with previous reports describing the fact that involvement of regions above the spinal cord may exist in HTLV-I—associated myelopathy. References 1. Gessain A, Barin F, Vernant JC, Gout O, Maurs L, Calender A. Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis . Lancet . 1985;2:407-410.Crossref 2. Rodgers-Johnson P, Gajdusek DC, Morgan OSC, Zaninovic V, Sarin PS, Graham DS. HTLV-I and HTLV-III antibodies and tropical spastic paraparesis . Lancet . 1985;2:1247-1248.Crossref 3. Vernant JC, Gessain A, Gout O, et al. Paraparésis spastiques tropicales en Martinique: haute prévalence d'anticorps HTLV-I . Presse Med . 1986;15:419-422. 4. Román GC. Retrovirus-associated myelopathies . Arch Neurol . 1987;44:659-663.Crossref 5. Román GC. The neuroepidemiology of tropical spastic paraparesis . Ann Neurol . 1988;23( (suppl) ):113-120.Crossref 6. Osame M, Usuku K, Izumo S, et al. HTLV-I associated myelopathy: a new clinical entity . Lancet . 1986;1:1031-1032.Crossref 7. Osame M, Matsumoto M, Usuku K, et al. Chronic progressive myelopathy associated with elevated antibodies to human T-lymphotropic virus type I and adult T-cell leukemia like cells . Ann Neurol . 1987;21:117-122.Crossref 8. Osame M, Igata A, Matsumoto M, Usuku K, Izumo S, Kosaka K. HTLV-I-associated myelopathy: a report of 85 cases . Ann Neurol . 1987;22:116. 9. Román GC, Osame M. Identity of HTLVI-associated tropical spastic paraparesis and HTLV-I-associated myelopathy . Lancet . 1988;1:651.Crossref 10. Osame M, Igata A, Matsumoto M, Usuku K, Kitajima I, Jakahashi K. On the discovery of a new clinical entity: human T-cell lymphotropic virus type I-associated myelopathy (HAM) . Shinkei Kenkyu Shinpo . 1987;31:727-745. 11. Arimura Y, Arimura K, Osame M, Igata A. Neuro-ophthalmological abnormalities in HTLVI associated myelopathy . Neuroophthalmology . 1987;7:243-248.Crossref 12. Shibasaki H, Kuroiwa Y. EEG abnormality in optic spinal form of multiple sclerosis . Eur Neurol . 1974;11:218-226.Crossref 13. Shibasaki H, Kuroiwa Y. EEG abnormality in multiple sclerosis, I: analysis based on our 30 autopsied or probable cases . Rinsho Shinkeigaku . 1973;13:477-483. 14. Hiyoshi T, Osame M, Moritoyo T, et al. Cystometric analysis of the urinary function of HTLV-I associated myelopathy: a preliminary report . Acta Med Univ Kogoshima . 1987;29( (pt 1) ):19-27. 15. Chatrian GE, Bergamini L, Dondey M, Klass DW, Lennox-Buchthal M, Petersen I. A glossary of terms most commonly used by clinical electroencephalographers . Electroencephalogr Clin Neurophysiol . 1974;37:538-548.Crossref 16. Arimura K, Rosales R, Osame M, Spencer PS, Schoenberg BS. Clinical electrophysiologic studies of HTLV-I-associated myelopathy . Arch Neurol . 1987;44:609-612.Crossref 17. Akizuki S, Nakazato O, Higuchi Y, et al. Necropsy findings in HTLV-I associated myelopathy . Lancet . 1987;1:156-157.Crossref 18. Montgomery RD, Cruickshank EK, Robertson WB, McMenemy WH. Clinical and pathological observations on Jamaican neuropathy: a report on 206 cases . Brain . 1964;87:425-462.Crossref 19. Román GC, Spencer PS, Schoenberg BS, et al. Tropical spastic paraparesis in the Seychelles Islands: a clinical and case-control neuroepidemiologic study . Neurology . 1987;37:1323-1328.Crossref 20. Robertson WB, Cruickshank EK. Jamaican (tropical) myeloneuropathy . In: Minckler J, ed. Pathology of the Nervous System . New York, NY: McGraw-Hill International Book Co; 1972;3:2466-2476. 21. Piccardo P, Ceroni M, Rodgers-Johnson P, et al. Pathological and immunological observations on tropical spastic paraparesis in patients from Jamaica . Ann Neurol . 1988;23( (suppl) ):156-160.Crossref 22. Newton M, Cruickshank K, Miller D, et al. Antibody to human T-lymphotropic virus type I in West Indian-born UK residents with spastic paraparesis . Lancet . 1987;1:415-416.Crossref 23. Bhagavati S, Ehrlich G, Kula RW, et al. Detection of human T-cell lymphoma/leukemia virus type I DNA and antigen in spinal fluid and blood of patients with chronic progressive myelopathy . N Engl J Med . 1988;318:1141-1147.Crossref 24. Furukawa Y, Une F, Osame M. Magnetic resonance imaging in HTLV-I-associated myelopathy. Rinsho Shinkei. In press. 25. Román GC, Schoenberg BS, Spencer PS, et al. Tropical spastic paraparesis (TSP) in the Seychelles Islands of the Indian Ocean: clinical, neurophysiologic, and pathologic features . Neurology . 1986;36( (suppl 1) ):106. Abstract.Crossref 26. Barkhause PE, Morgan O. Jamaican neuropathy: an electrophysiological study . Muscle Nerve . 1988;11:380-385.Crossref 27. Ludolph AC, Hugon J, Román GC, et al. A clinical neurophysiologic study of tropical spastic paraparesis . Muscle Nerve . 1988;11:392-397.Crossref

Journal

Archives of NeurologyAmerican Medical Association

Published: May 1, 1989

References