ORIGINAL CONTRIBUTION Elective Intra-aortic Balloon Counterpulsation During High-Risk Percutaneous Coronary Intervention A Randomized Controlled Trial Divaka Perera, MD, MRCP Context Observational studies have previously reported that elective intra-aortic bal- Rodney Stables, DM, FRCP loon pump (IABP) insertion may improve outcomes following high-risk percutaneous coronary intervention (PCI). To date, this assertion has not been tested in a random- Martyn Thomas, MD, FRCP ized trial. Jean Booth, MSc Objective To determine whether routine intra-aortic balloon counterpulsation be- Michael Pitt, MD, FRCP fore PCI reduces major adverse cardiac and cardiovascular events (MACCE) in pa- tients with severe left ventricular dysfunction and extensive coronary disease. Daniel Blackman, MD, MRCP Design, Setting, and Patients The Balloon Pump–Assisted Coronary Interven- Adam de Belder, MD, FRCP tion Study, a prospective, open, multicenter, randomized controlled trial conducted in Simon Redwood, MD, FRCP 17 tertiary referral cardiac centers in the United Kingdom between December 2005 for the BCIS-1 Investigators and January 2009. Patients (n = 301) had severe left ventricular dysfunction (ejection fraction 30%) and extensive coronary disease ( Jeopardy Score 8/12); those with contraindications to or class I indications for IABP therapy were excluded. ERCUTANEOUS CORONARY IN- tervention (PCI) in patients Intervention Elective insertion of IABP before
JAMA – American Medical Association
Published: Aug 25, 2010
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