Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

EFFECTS OF NASAL INHALERS ON ERECTILE TISSUES OF THE NOSE: QUANTITATIVE STUDIES

EFFECTS OF NASAL INHALERS ON ERECTILE TISSUES OF THE NOSE: QUANTITATIVE STUDIES Abstract The introduction of the nasal inhaler into the field of rhinologic therapy has met with widespread acceptance by both the physician and the public. The nasal inhaler offers a simple and inexpensive method of obtaining symptomatic relief from the nasal congestion that accompanies rhinitis. It has the advantages of simplicity of use, compactness and efficiency of response. Many types of inhalers are now commercially available. Some contain powerful vasoconstrictor drugs, such as amphetamine, while others contain classic rhinologic remedies, such as menthol, camphor and oil of eucalyptus. Peters and Faulkner1 studied the effects of volatile amphetamine on the pulse, the blood pressure and the electrocardiogram of human subjects with various pathologic conditions. They used doses larger than the therapeutic amounts employed in rhinologic practice. They concluded that the drug produced no significant changes in the pulse or the blood pressure and only slight alterations in the electrocardiogram. They warned, however, References 1. Peters, C. M., and Faulkner, J. M.: Circulatory Effects of Volatile Amphetamine (Benzedrine Inhaler) , Am. J. M. Sc. 198:104 ( (July) ) 1939.Crossref 2. Bertolet, J. A.: Benzyl Methyl Carbinamine Carbonate , M. J. & Rec. 136:75 ( (July) ) 1932. 3. Sternstein, H. J.: Efficacy of Vasoconstrictor Agents in the Obstructed Nose: A Quantitative Evaluation , Arch. Otolaryng. 36:713 ( (Nov.) ) 1942. 4. Sternstein, H. J., and Schur, M. O.: Quantitative Study of Nasal Obstruction: A New Method , Arch. Otolaryng. 23:475 ( (April) ) 1936. 5. The drugs used in these experiments, with the exception of commercial products, were furnished by Dr. D. L. Tabern, of the Abbott Laboratories, North Chicago, Ill. 6. Tabern, D. L.: Personal communication to the authors. 7. The commercial amphetamine inhaler used is manufactured by Smith, Kline & French Laboratories, Fifth and Arch Sts., Philadelphia, and is marketed under the name "benzedrine inhaler." 8. Astrotone, a perfume fixative, is manufactured by E. I. duPont de Nemours & Co., Inc., Aromatic Section, 40 Worth St., New York. 9. The synthetic perfume N.W.C. is manufactured by Fulton Chemical Co., Inc., 599 Johnson Ave., Brooklyn. 10. There are various menthol type inhalers. The one used in these experiments manufactured by Vicks Chemical Company and is marketed under the name "Vicks Inhaler." 11. Fox, N.: Effect of Camphor, Eucalyptol and Menthol on the Vascular State of the Mucous Membrane , Arch. Otolaryng. 6:112 ( (Aug.) ) 1927. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

EFFECTS OF NASAL INHALERS ON ERECTILE TISSUES OF THE NOSE: QUANTITATIVE STUDIES

Archives of Otolaryngology , Volume 38 (4) – Oct 1, 1943

Loading next page...
 
/lp/american-medical-association/effects-of-nasal-inhalers-on-erectile-tissues-of-the-nose-quantitative-OAFWxGjJJ5
Publisher
American Medical Association
Copyright
Copyright © 1943 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1943.00670040323001
Publisher site
See Article on Publisher Site

Abstract

Abstract The introduction of the nasal inhaler into the field of rhinologic therapy has met with widespread acceptance by both the physician and the public. The nasal inhaler offers a simple and inexpensive method of obtaining symptomatic relief from the nasal congestion that accompanies rhinitis. It has the advantages of simplicity of use, compactness and efficiency of response. Many types of inhalers are now commercially available. Some contain powerful vasoconstrictor drugs, such as amphetamine, while others contain classic rhinologic remedies, such as menthol, camphor and oil of eucalyptus. Peters and Faulkner1 studied the effects of volatile amphetamine on the pulse, the blood pressure and the electrocardiogram of human subjects with various pathologic conditions. They used doses larger than the therapeutic amounts employed in rhinologic practice. They concluded that the drug produced no significant changes in the pulse or the blood pressure and only slight alterations in the electrocardiogram. They warned, however, References 1. Peters, C. M., and Faulkner, J. M.: Circulatory Effects of Volatile Amphetamine (Benzedrine Inhaler) , Am. J. M. Sc. 198:104 ( (July) ) 1939.Crossref 2. Bertolet, J. A.: Benzyl Methyl Carbinamine Carbonate , M. J. & Rec. 136:75 ( (July) ) 1932. 3. Sternstein, H. J.: Efficacy of Vasoconstrictor Agents in the Obstructed Nose: A Quantitative Evaluation , Arch. Otolaryng. 36:713 ( (Nov.) ) 1942. 4. Sternstein, H. J., and Schur, M. O.: Quantitative Study of Nasal Obstruction: A New Method , Arch. Otolaryng. 23:475 ( (April) ) 1936. 5. The drugs used in these experiments, with the exception of commercial products, were furnished by Dr. D. L. Tabern, of the Abbott Laboratories, North Chicago, Ill. 6. Tabern, D. L.: Personal communication to the authors. 7. The commercial amphetamine inhaler used is manufactured by Smith, Kline & French Laboratories, Fifth and Arch Sts., Philadelphia, and is marketed under the name "benzedrine inhaler." 8. Astrotone, a perfume fixative, is manufactured by E. I. duPont de Nemours & Co., Inc., Aromatic Section, 40 Worth St., New York. 9. The synthetic perfume N.W.C. is manufactured by Fulton Chemical Co., Inc., 599 Johnson Ave., Brooklyn. 10. There are various menthol type inhalers. The one used in these experiments manufactured by Vicks Chemical Company and is marketed under the name "Vicks Inhaler." 11. Fox, N.: Effect of Camphor, Eucalyptol and Menthol on the Vascular State of the Mucous Membrane , Arch. Otolaryng. 6:112 ( (Aug.) ) 1927.

Journal

Archives of OtolaryngologyAmerican Medical Association

Published: Oct 1, 1943

References