PRELIMINARY COMMUNICATION Effects of Dietary Composition on Energy Expenditure During Weight-Loss Maintenance Cara B. Ebbeling, PhD Context Reduced energy expenditure following weight loss is thought to contrib- ute to weight gain. However, the effect of dietary composition on energy expendi- Janis F. Swain, MS, RD ture during weight-loss maintenance has not been studied. Henry A. Feldman, PhD Objective To examine the effects of 3 diets differing widely in macronutrient com- William W. Wong, PhD position and glycemic load on energy expenditure following weight loss. David L. Hachey, PhD Design, Setting, and Participants A controlled 3-way crossover design involv- Erica Garcia-Lago, BA ing 21 overweight and obese young adults conducted at Children’s Hospital Boston and Brigham and Women’s Hospital, Boston, Massachusetts, between June 16, 2006, David S. Ludwig, MD, PhD and June 21, 2010, with recruitment by newspaper advertisements and postings. ANY PEOPLE CAN LOSE Intervention After achieving 10% to 15% weight loss while consuming a run-in weight for a few months, diet, participants consumed an isocaloric low-fat diet (60% of energy from carbohy- but most have difficulty drate, 20% from fat, 20% from protein; high glycemic load), low–glycemic index diet (40% from carbohydrate, 40% from fat, and 20% from
JAMA – American Medical Association
Published: Jun 27, 2012
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