ARTICLE Effects of a Minimum Interval Immunization Schedule for Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccination During a Pertussis Outbreak Daniel Bronson-Lowe, PhD; Shoana M. Anderson, MPH Objective: To examine the impact of a minimum in- interval group) compared with children who received all terval schedule for administering diphtheria and teta- doses of DTaP on the standard childhood and adoles- nus toxoids and acellular pertussis vaccine (DTaP) in in- cent immunization schedule (standard group). fants during a statewide pertussis outbreak on receipt of inactivated polio vaccine (IPV) and pneumococcal con- Outcome Measures: Timing and receipt of 3 doses of jugate vaccine (PCV). the DTaP, IPV, and PCV. Design: Retrospective cohort study using the state im- Results: Compared with children in the standard group, munization registry. children in the minimum interval group were more likely to receive 3 doses of DTaP (relative risk, 1.34; 95% con- Setting: Arizona. fidence interval, 1.32-1.35), 3 doses of IPV (1.27; 1.25- 1.29), and 3 doses of PCV (1.37; 1.35-1.39). Participants: Arizona children born between Febru- ary 1 and September 30, 2005, who received their initial Conclusion: Recommending a minimum interval DTaP DTaP dose during a statewide pertussis outbreak schedule during a statewide pertussis
JAMA Pediatrics – American Medical Association
Published: May 1, 2009
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