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Effectiveness of Treatment for Sudden Sensorineural Hearing Loss

Effectiveness of Treatment for Sudden Sensorineural Hearing Loss CLINICAL CHALLENGES IN OTOLARYNGOLOGY SECTION EDITOR: KAREN H. CALHOUN, MD; ASSISTANT SECTION EDITOR: RONALD B. KUPPERSMITH, MD Effectiveness of Treatment for Sudden Sensorineural Hearing Loss David J. Eisenman, MD; H. Alexander Arts, MD Hypothesis: Sudden-onset unilat- eral sensorineural hearing loss has no effective treatment. BACKGROUND The phenomenon of sudden-onset, unilateral sensorineural hearing loss (SSNHL) has been recognized and well described for some time. Whether it represents a single patho- physiologic entity or is the com- mon end point of numerous, var- David J. Eisenman, MD H. Alexander Arts, MD ied pathologic processes remains unknown. Many different causes of SSNHL have been hypothesized: vi- certain subsets of patients. This rate decibels, analysis of percent improve- ral infection of the labyrinth or co- is usually estimated at about 65%. Be- ment relative to the unaffected ear, chlear nerve; vascular insult; peri- cause of the high rate of spontane- and semiquantitative grading of im- lymphatic hypoxia; intralabyrinthine ous resolution, well-controlled stud- provement (complete, good, fair, membrane rupture; inflammatory ies with comparisons of patients poor, or none) based on composite and metabolic causes; and others. randomized to treatment and pla- ipsilateral and contralateral audio- However, none has been shown to cebo groups are http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Otolaryngology - Head & Neck Surgery American Medical Association

Effectiveness of Treatment for Sudden Sensorineural Hearing Loss

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Publisher
American Medical Association
Copyright
Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6181
eISSN
2168-619X
DOI
10.1001/archotol.126.9.1161
Publisher site
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Abstract

CLINICAL CHALLENGES IN OTOLARYNGOLOGY SECTION EDITOR: KAREN H. CALHOUN, MD; ASSISTANT SECTION EDITOR: RONALD B. KUPPERSMITH, MD Effectiveness of Treatment for Sudden Sensorineural Hearing Loss David J. Eisenman, MD; H. Alexander Arts, MD Hypothesis: Sudden-onset unilat- eral sensorineural hearing loss has no effective treatment. BACKGROUND The phenomenon of sudden-onset, unilateral sensorineural hearing loss (SSNHL) has been recognized and well described for some time. Whether it represents a single patho- physiologic entity or is the com- mon end point of numerous, var- David J. Eisenman, MD H. Alexander Arts, MD ied pathologic processes remains unknown. Many different causes of SSNHL have been hypothesized: vi- certain subsets of patients. This rate decibels, analysis of percent improve- ral infection of the labyrinth or co- is usually estimated at about 65%. Be- ment relative to the unaffected ear, chlear nerve; vascular insult; peri- cause of the high rate of spontane- and semiquantitative grading of im- lymphatic hypoxia; intralabyrinthine ous resolution, well-controlled stud- provement (complete, good, fair, membrane rupture; inflammatory ies with comparisons of patients poor, or none) based on composite and metabolic causes; and others. randomized to treatment and pla- ipsilateral and contralateral audio- However, none has been shown to cebo groups are

Journal

JAMA Otolaryngology - Head & Neck Surgery – American Medical Association

Published: Sep 1, 2000

References

  • Sudden hearing loss: eight years' experience and suggested prognostic table.
    Byl, FM
  • Natural history of sudden sensorineural hearing loss.
    Mattox, DE; Simmons, FB
  • Evaluation of a "shotgun" regimen for sudden hearing loss.
    Wilkins, SA; Mattox, DE; Lyles, A
  • Treatment of idiopathic sudden sensorineural hearing loss.
    Grandis, JR; Hirsch, BE; Wagener, MM