Key PointsQuestionDoes routine prophylactic low-dose oxygen supplementation after acute stroke improve functional outcome? FindingsIn this randomized clinical trial, 8003 patients with acute stroke were randomized within 24 hours of admission to 3 days of continuous oxygen, nocturnal oxygen, or control. After 3 months, there was no significant difference in death and disability for the combined oxygen groups compared with control (odds ratio, 0.97) or for the continuous oxygen group compared with the nocturnal oxygen group (odds ratio, 1.03). MeaningRoutine low-dose oxygen did not improve outcomes in nonhypoxic patients after acute stroke.
JAMA – American Medical Association
Published: Sep 26, 2017
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