Key PointsQuestionIs repetitive transcranial magnetic stimulation an efficacious treatment for treatment-resistant major depression in patients who are veterans? FindingsIn this randomized clinical trial of 164 US veterans with depression, the overall remission rate was 39%, with no significant difference between the active and sham groups. Patients with comorbid posttraumatic stress disorder showed the least improvement. MeaningThese findings may reflect the importance of close clinical surveillance, rigorous monitoring of concomitant medication, and regular interaction with clinic staff in bringing about significant improvement in this treatment-resistant population.
JAMA Psychiatry – American Medical Association
Published: Sep 27, 2018
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