Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Effect of Nebulized Magnesium vs Placebo Added to Albuterol on Hospitalization Among Children With Refractory Acute Asthma Treated in the Emergency Department

Effect of Nebulized Magnesium vs Placebo Added to Albuterol on Hospitalization Among Children... Key PointsQuestionWhat is the effectiveness of nebulized magnesium in children and adolescents with acute asthma in the emergency department who remain in moderate or severe respiratory distress after evidence-based standardized initial therapy? FindingsIn this randomized clinical trial that included 816 patients, nebulized magnesium with albuterol, compared with placebo with albuterol, did not significantly decrease the rate of hospitalization for asthma within 24 hours (43.5% vs 47.7%, respectively). MeaningThe findings do not support use of nebulized magnesium with albuterol among children with refractory acute asthma. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Loading next page...
 
/lp/american-medical-association/effect-of-nebulized-magnesium-vs-placebo-added-to-albuterol-on-ZwiW0LXdrk
Publisher
American Medical Association
Copyright
Copyright 2020 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2020.19839
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionWhat is the effectiveness of nebulized magnesium in children and adolescents with acute asthma in the emergency department who remain in moderate or severe respiratory distress after evidence-based standardized initial therapy? FindingsIn this randomized clinical trial that included 816 patients, nebulized magnesium with albuterol, compared with placebo with albuterol, did not significantly decrease the rate of hospitalization for asthma within 24 hours (43.5% vs 47.7%, respectively). MeaningThe findings do not support use of nebulized magnesium with albuterol among children with refractory acute asthma.

Journal

JAMAAmerican Medical Association

Published: Nov 24, 2020

References