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Effect of Ligation of Pancreatic Ducts on Chronic Pancreatitis: Experimental Study

Effect of Ligation of Pancreatic Ducts on Chronic Pancreatitis: Experimental Study Abstract There is no universally effective form of therapy in the treatment of chronic pancreatitis. To be sure, some of the patients with this condition experience temporary remission or are helped by the various procedures currently in use. When there is coexisting disease of the biliary tract, cholecystectomy and T-tube drainage of the common duct, or sphincterotomy, may control further exacerbations of pancreatitis. When pancreatic lithiasis or intermittent obstruction of the pancreatic duct or ducts exist, drainage of the ducts of the pancreas sometimes affords satisfactory control. However, there remains a group of patients for whom these surgical measures fail to halt the devastating exacerbations of chronic pancreatitis. It is in these patients that subtotal or total pancreatectomy has been advocated and used with considerable success. Both subtotal and total pancreatectomy are formidable procedures and carry with them high operative morbidity and mortality rates. What is needed then is a procedure References 1. Banting, F. G., and Best, C. H.: The Internal Secretion of the Pancreas , J. Lab. Clin. Med. 7:251-266 ( (Feb.) ) 1922. 2. Cannon, J. A.: Experience with Ligation of the Pancreatic Ducts in the Treatment of Chronic Relapsing Pancreatitis , Amer. J. Surg. 90:266-280 ( (Aug.) ) 1955.Crossref 3. Carnevali, J. F.; ReMine, W. H.; Dockerty, M. B.; Bollman, J. L., and Grindlay, J. H.: An Experimental Study of Side-to-Side Pancreaticojejunostomy After Ductal Obstruction , A.M.A. Arch. Surg. 80:774-787 ( (May) ) 1960.Crossref 4. Martin, L., and Canseco, J. D.: Pancreatic Calculosis , J.A.M.A. 135:1055-1060 ( (Dec. 20) ) 1947.Crossref 5. Rienhoff, W. F., quoted by Martin, L., and Canseco, J. D.4 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Effect of Ligation of Pancreatic Ducts on Chronic Pancreatitis: Experimental Study

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Publisher
American Medical Association
Copyright
Copyright © 1962 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1962.01310060167032
Publisher site
See Article on Publisher Site

Abstract

Abstract There is no universally effective form of therapy in the treatment of chronic pancreatitis. To be sure, some of the patients with this condition experience temporary remission or are helped by the various procedures currently in use. When there is coexisting disease of the biliary tract, cholecystectomy and T-tube drainage of the common duct, or sphincterotomy, may control further exacerbations of pancreatitis. When pancreatic lithiasis or intermittent obstruction of the pancreatic duct or ducts exist, drainage of the ducts of the pancreas sometimes affords satisfactory control. However, there remains a group of patients for whom these surgical measures fail to halt the devastating exacerbations of chronic pancreatitis. It is in these patients that subtotal or total pancreatectomy has been advocated and used with considerable success. Both subtotal and total pancreatectomy are formidable procedures and carry with them high operative morbidity and mortality rates. What is needed then is a procedure References 1. Banting, F. G., and Best, C. H.: The Internal Secretion of the Pancreas , J. Lab. Clin. Med. 7:251-266 ( (Feb.) ) 1922. 2. Cannon, J. A.: Experience with Ligation of the Pancreatic Ducts in the Treatment of Chronic Relapsing Pancreatitis , Amer. J. Surg. 90:266-280 ( (Aug.) ) 1955.Crossref 3. Carnevali, J. F.; ReMine, W. H.; Dockerty, M. B.; Bollman, J. L., and Grindlay, J. H.: An Experimental Study of Side-to-Side Pancreaticojejunostomy After Ductal Obstruction , A.M.A. Arch. Surg. 80:774-787 ( (May) ) 1960.Crossref 4. Martin, L., and Canseco, J. D.: Pancreatic Calculosis , J.A.M.A. 135:1055-1060 ( (Dec. 20) ) 1947.Crossref 5. Rienhoff, W. F., quoted by Martin, L., and Canseco, J. D.4

Journal

Archives of SurgeryAmerican Medical Association

Published: Dec 1, 1962

References