Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Effect of Ivermectin on Time to Resolution of Symptoms Among Adults With Mild COVID-19

Effect of Ivermectin on Time to Resolution of Symptoms Among Adults With Mild COVID-19 Key PointsQuestionWhat is the effect of ivermectin on duration of symptoms in adults with mild COVID-19? FindingsIn this randomized clinical trial that included 476 patients, the duration of symptoms was not significantly different for patients who received a 5-day course of ivermectin compared with placebo (median time to resolution of symptoms, 10 vs 12 days; hazard ratio for resolution of symptoms, 1.07). MeaningThe findings do not support the use of ivermectin for treatment of mild COVID-19, although larger trials may be needed to understand effects on other clinically relevant outcomes. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Loading next page...
 
/lp/american-medical-association/effect-of-ivermectin-on-time-to-resolution-of-symptoms-among-adults-GzS1hzl2zx
Publisher
American Medical Association
Copyright
Copyright 2021 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2021.3071
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionWhat is the effect of ivermectin on duration of symptoms in adults with mild COVID-19? FindingsIn this randomized clinical trial that included 476 patients, the duration of symptoms was not significantly different for patients who received a 5-day course of ivermectin compared with placebo (median time to resolution of symptoms, 10 vs 12 days; hazard ratio for resolution of symptoms, 1.07). MeaningThe findings do not support the use of ivermectin for treatment of mild COVID-19, although larger trials may be needed to understand effects on other clinically relevant outcomes.

Journal

JAMAAmerican Medical Association

Published: Apr 13, 2021

References