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EFFECT OF INJECTIONS OF COLLOIDAL THORIUM DIOXIDE ON THE VENTRICLES AND SUBARACHNOID SPACES

EFFECT OF INJECTIONS OF COLLOIDAL THORIUM DIOXIDE ON THE VENTRICLES AND SUBARACHNOID SPACES Abstract In the course of studies1 on the use of colloidal thorium dioxide as an agent for ventriculography a number of surgical and pathologic specimens have been obtained, from which some conclusions may be drawn concerning the effects produced by the injection of this foreign substance. As far as I am aware, there have been no similar studies of the results in man, and the studies on dogs reported by Alexander, Jung and Lyman2 were made after the intraventricular injection of an unstabilized and unbuffered colloidal suspension of thorium dioxide. In view of the remarkable ventriculograms obtained after the injection of colloidal thorium dioxide, information is desirable to indicate whether the method is a safe one for more extensive use. The material on which I am reporting consisted of two specimens obtained for biopsy and material from eight autopsies, the time of securing of which ranged from one hour References 1. Freeman, W.; Schoenfeld, H. H., and Moore, C.: Ventriculography with Colloidal Thorium Dioxide Solution , J. A. M. A. 106:96 ( (Jan. 11) ) 1936.Crossref 2. Alexander, L.; Jung, T. S., and Lyman, R. S.: Colloidal Thorium Dioxide: Its Use in Intracranial Diagnosis and Its Fate on Direct Injection into the Brain and the Ventricles , Arch. Neurol. & Psychiat. 32:1143 ( (Dec.) ) 1934. 3. Lange, O.: Considérations sur l'éosinophilie du liquide céphalorachidien , Rev. neurol. 64:512 ( (Oct.) ) 1935. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology & Psychiatry American Medical Association

EFFECT OF INJECTIONS OF COLLOIDAL THORIUM DIOXIDE ON THE VENTRICLES AND SUBARACHNOID SPACES

Archives of Neurology & Psychiatry , Volume 38 (2) – Aug 1, 1937

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Publisher
American Medical Association
Copyright
Copyright © 1937 American Medical Association. All Rights Reserved.
ISSN
0096-6754
DOI
10.1001/archneurpsyc.1937.02260200112009
Publisher site
See Article on Publisher Site

Abstract

Abstract In the course of studies1 on the use of colloidal thorium dioxide as an agent for ventriculography a number of surgical and pathologic specimens have been obtained, from which some conclusions may be drawn concerning the effects produced by the injection of this foreign substance. As far as I am aware, there have been no similar studies of the results in man, and the studies on dogs reported by Alexander, Jung and Lyman2 were made after the intraventricular injection of an unstabilized and unbuffered colloidal suspension of thorium dioxide. In view of the remarkable ventriculograms obtained after the injection of colloidal thorium dioxide, information is desirable to indicate whether the method is a safe one for more extensive use. The material on which I am reporting consisted of two specimens obtained for biopsy and material from eight autopsies, the time of securing of which ranged from one hour References 1. Freeman, W.; Schoenfeld, H. H., and Moore, C.: Ventriculography with Colloidal Thorium Dioxide Solution , J. A. M. A. 106:96 ( (Jan. 11) ) 1936.Crossref 2. Alexander, L.; Jung, T. S., and Lyman, R. S.: Colloidal Thorium Dioxide: Its Use in Intracranial Diagnosis and Its Fate on Direct Injection into the Brain and the Ventricles , Arch. Neurol. & Psychiat. 32:1143 ( (Dec.) ) 1934. 3. Lange, O.: Considérations sur l'éosinophilie du liquide céphalorachidien , Rev. neurol. 64:512 ( (Oct.) ) 1935.

Journal

Archives of Neurology & PsychiatryAmerican Medical Association

Published: Aug 1, 1937

References