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Key PointsQuestionDoes treatment with hydroxychloroquine improve clinical outcomes of adults hospitalized with coronavirus disease 2019 (COVID-19)? FindingsIn this randomized clinical trial that included 479 hospitalized adults with respiratory symptoms from COVID-19, the distribution of the day 14 clinical status score (measured using a 7-category ordinal scale) was not significantly different for patients randomized to receive hydroxychloroquine compared with placebo (adjusted odds ratio, 1.02). MeaningThese findings do not support the use of hydroxychloroquine for treatment of COVID-19 among hospitalized adults.
JAMA – American Medical Association
Published: Dec 1, 2020
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