Key PointsQuestionDo aerobic exercise and escitalopram reduce anxiety and improve coronary heart disease biomarkers more than a placebo? FindingsIn this randomized clinical trial including 128 patients with coronary heart disease and anxiety, escitalopram, but not exercise, resulted in reduced levels of anxiety and depression compared with a placebo control. MeaningFor patients in this study with coronary heart disease and high anxiety, escitalopram was an effective treatment for reducing anxiety, although the extent to which this benefit may improve clinical outcomes remains uncertain.
JAMA Psychiatry – American Medical Association
Published: Nov 18, 2021
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