Key PointsQuestionIn patients with suspected coronary heart disease, does a strategy involving cardiovascular magnetic resonance (CMR) result in less unnecessary angiography than a myocardial perfusion scintigraphy (MPS) strategy or a national guideline that included sending high-risk patients directly to angiography? FindingsIn this clinical trial, both CMR and MPS strategies significantly reduced unnecessary angiography rates compared with national guidelines (7.5% for CMR, 7.1% for MPS, 28.8% for national guidelines); no statistically significant differences were seen between CMR and MPS strategies. There was no statistically significant difference in major cardiovascular event rates at 12 months between the 3 groups. MeaningNoninvasive functional imaging strategies reduced unnecessary angiography compared with guidelines-directed care.
JAMA – American Medical Association
Published: Sep 13, 2016