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- Publisher
- American Medical Association
- Copyright
- Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
- ISSN
- 2168-6203
- eISSN
- 2168-6211
- DOI
- 10.1001/archpediatrics.2009.148
- pmid
- 19736336
- Publisher site
- See Article on Publisher Site
Abstract
ARTICLE Effect of Android to Gynoid Fat Ratio on Insulin Resistance in Obese Youth Julien Aucouturier, MSc; Martine Meyer, MD; David Thivel, MSc; Michel Taillardat, MD; Pascale Duche´, PhD Background: Upper body fat distribution is associ- energy x-ray absorptiometry. Insulin resistance was as- ated with the early development of insulin resistance in sessed by the homeostasis model of insulin resistance obese children and adolescents. (HOMA-IR) index. Objective:: To determine if an android to gynoid fat ra- Results: There were no differences in weight, body mass tio is associated with the severity of insulin resistance in index, and body fat percentage between tertiles. Values obese children and adolescents, whereas peripheral sub- of HOMA-IR were significantly increased in the 2 higher cutaneous fat may have a protective effect against insu- tertiles (mean [SD], tertile 2, 2.73 [1.41]; tertile 3, 2.89 lin resistance. [1.28]) compared with the lower tertile (tertile 1, 1.67 [1.24]) of android to gynoid fat ratio (P .001). The Setting: The pediatric department of University Hos- HOMA-IR value was significantly associated with an- pital, Clermont-Ferrand, France. droid to gynoid fat ratio (r = 0.35; P .01). Design: A retrospective analysis using data from medi- Conclusions: Android fat distribution is
Journal
JAMA Pediatrics – American Medical Association
Published: Sep 1, 2009