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Effect of a Low Free Sugar Diet vs Usual Diet on Nonalcoholic Fatty Liver Disease in Adolescent Boys

Effect of a Low Free Sugar Diet vs Usual Diet on Nonalcoholic Fatty Liver Disease in Adolescent Boys Key PointsQuestionDoes restricting dietary free sugars reduce hepatic steatosis in children with nonalcoholic fatty liver disease? FindingsIn this randomized clinical trial that included 40 adolescent boys aged 11 to 16 years with nonalcoholic fatty liver disease followed up for 8 weeks, provision of a diet low in free sugars compared with usual diet resulted in a greater reduction in hepatic steatosis from 25% to 17% in the low free sugar diet group and from 21% to 20% in the usual diet group, a statistically significant difference of −6.23% when adjusted for baseline. MeaningThese preliminary findings suggest potential benefit of a diet low in free sugars for children with nonalcoholic fatty liver disease, but further research is needed to assess long-term and clinical outcomes. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2019 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2018.20579
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionDoes restricting dietary free sugars reduce hepatic steatosis in children with nonalcoholic fatty liver disease? FindingsIn this randomized clinical trial that included 40 adolescent boys aged 11 to 16 years with nonalcoholic fatty liver disease followed up for 8 weeks, provision of a diet low in free sugars compared with usual diet resulted in a greater reduction in hepatic steatosis from 25% to 17% in the low free sugar diet group and from 21% to 20% in the usual diet group, a statistically significant difference of −6.23% when adjusted for baseline. MeaningThese preliminary findings suggest potential benefit of a diet low in free sugars for children with nonalcoholic fatty liver disease, but further research is needed to assess long-term and clinical outcomes.

Journal

JAMAAmerican Medical Association

Published: Jan 22, 2019

References

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