Eczematous Changes on the Hands—Diagnosis
Abstract
Diagnosis: “Mechanic’s hands” as part of the antisynthetase syndrome. Microscopic findings and clinical course Histologic examination of the biopsy specimen revealed psoriasiform acanthosis with thick parakeratosis. A heavy lymphohistiocytic infiltrate in the upper dermis was noted, along with an interface dermatitis with occasional colloid bodies. Lymphocyte exocytosis was seen. Our patient experienced little benefit from treatment with a variety of topical agents,...