Abstract Long-term follow-up was obtained on 138 patients who participated in a prospective, randomized study comparing two weeks with three weeks of hospitalization following uncomplicated acute myocardial infarction. Follow-up information was available on 123 (89%) of all randomized patients. The mean follow-up period was 35 months for those patients who died and 99 months for those who survived. No differences were found between the two groups with respect to survival, cardiac-related deaths, frequency or severity of angina pectoris, subsequent myocardial infarction, incidence of congestive heart failure, number of ventricular aneurysms, or subsequent medical therapy. A significantly greater number of survivors in both groups stopped smoking and had a normal initial heart size than those who died. This long-term follow-up study further supports the conclusions of earlier short-term studies that two weeks of hospitalization is safe in patients with uncomplicated acute myocardial infarction. (Arch Intern Med 1982;142:875-878) References 1. Hutter AM Jr, Sidel VW, Shine KI, et al: Early hospital discharge after myocardial infarction. N Engl J Med 1973;288:1141-1144.Crossref 2. McNeer JF, Wagner GS, Ginsburg PB, et al: Hospital discharge one week after acute myocardial infarction. N Engl J Med 1978;298:229-232.Crossref 3. Harpur JE, Conner WT, Hamilton M, et al: Early mobilization and discharge from hospital in uncomplicated myocardial infarction. Lancet 1971;2:1331-1334.Crossref 4. Harpur JE: Shorter hospitalization for myocardial infarcts. N Engl J Med 1973;289:805.Crossref 5. Bloch A, Maeder J-P, Haissly J-C, et al: Early mobilization after myocardial infarction: A controlled study. Am J Cardiol 1974;34:152-157.Crossref 6. Hayes MJ, Marris GK, Hampton JR: Comparison of mobilization after two and nine days in uncomplicated myocardial infarction. Br Med J 1974;2:10-13.Crossref 7. Swan HJC, Blackburn HW, DeSanctis RW, et al: Duration of hospitalization in 'uncomplicated completed acute myocardial infarction': An ad hoc committee review. Am J Cardiol 1976;37:413-419.Crossref 8. Abraham AS, Sever Y, Weinstein M, et al: Value of early ambulation in patients with and without complications after myocardial infarction. N Engl J Med 1975;292:719-722.Crossref 9. McNeer JF, Wallace AG, Wagner GS, et al: The course of acute myocardial infarction: Feasibility of early discharge of the uncomplicated patient. Circulation 1975;51:410-413.Crossref 10. Oberman A, Jones WB, Riley CP: Natural history of coronary artery disease. Bull NY Acad Med 1972;48:1109-1125. 11. Slone D, Shapiro S, Rosenbert L, et al: Relation of cigarette smoking to myocardial infarction in young women. N Engl J Med 1978;298:1273-1276.Crossref 12. Dall R, Peto R: Mortality in relation to smoking: 20 years' observations on male British doctors. Br Med J 1976;2:1525-1536.Crossref 13. Wilhelmsson C, Elmfeldt D, Vedin JA, et al: Smoking and myocardial infarction. Lancet 1975;1:415-419.Crossref 14. Mulcahy R, Graham I, Hickey N: Influence of cigarette smoking on morbidity, mortality, and mode of death in coronary patients, abstracted. Br Heart J 1979;41:365.
Archives of Internal Medicine – American Medical Association
Published: May 1, 1982