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Dystonia Musculorum Deformans Alleviated by Chemopallidectomy and Chemopallidothalamectomy

Dystonia Musculorum Deformans Alleviated by Chemopallidectomy and Chemopallidothalamectomy Abstract Of the many neurologic diseases which have failed to respond to medical or surgical therapeutic measures, the extrapyramidal disorders of childhood have, by and large, been considered as the most intractable, and have generally been regarded as hopeless. In 1951 Percival Bailey stated that "on the whole surgery has little application in the vast field of the extrapyramidal hyperkinesias." However, in the brief six years since this statement was made, considerable progress has been made as regards the possibilities for the surgical therapy of tremor and rigidity in the adult Parkinsonian patient. Our own series (St. Barnabas Hospital) of 800 cases of Parkinsonism treated by anterior choroidal artery occlusion (50 cases) and chemopallidectomy (750 cases) demonstrates that both tremor and rigidity can be alleviated without any neurologic sacrifice by the infliction of well-localized but sufficient-sized lesions in the globus pallidus and/or the ventrolateral nucleus of the thalamus. Similar progress has References 1. Deaver, G.: Cerebral Palsy: Methods of Evaluation and Treatment , Rehabilitation Monograph IX, New York, Institute of Physical Medicine and Rehabilitation, New York University-Bellevue Medical Center, 1955. 2. Parker, H. L.: Clinical Studies in Neurology , Springfield, Ill., Charles C Thomas, Publisher, 1956. 3. Meyers, R.: Surgical Experiments in Therapy of Certain "Extrapyramidal" Diseases: Current Evaluation , Acta psychiat. et neurol. , (Supp. 67) , pp. 3-42, 1951. 4. Meyers, R., in Clinical Neurology , edited by A. B. Baker, New York, Paul B. Hoeber, Inc., (medical book department of Harper & Brothers), 1955, Vol. 2, pp. 1107-1159. 5. Meyers, R.: Results of Bilateral Intermediate Midbrain Crusotomy in 7 Cases of Severe Athetotic and Dystonic Quadriparesis , Am. J. Phys. Med. 35: 84-105 ( (April) ) 1956. 6. Grinker, R. R., and Bucy, P. C.: Neurology , Ed. 4, Springfield, Ill., Charles C Thomas, Publisher, 1949. 7. Cooper, I. S.: Intracerebral Injection of Procaine into the Globus Pallidus in Hyperkinetic Disorders , Science 119:417-418 ( (March 26) ) 1954.Crossref 8. Cooper, I. S.: Chemopallidectomy: Investigative Technique in Geriatric Parkinsonians , Science 121:217-218 ( (Feb. 11) ) 1955.Crossref 9. Cooper, I. S.; Poloukhine, N., and Hoen, T. I.: Chemopallidectomy for Dystonia Musculorum Deformans , J. Am. Geriatrics Soc. 4:1208-1213 ( (Dec.) ) 1956. 10. Bravo, G., and Cooper, I. S.: Chemopallidectomy—Two Recent Technical Additions , J. Am. Geriatric Soc. 5:651-655 ( (July) ) 1957. 11. Gass, H.: Personal communication to the author. 12. Cooper, I. S.: Relief of Juveline Involuntary Movement Disorders by Chemopallidectomy , J. A. M. A. 164:1297-1301 ( (July 20) ) 1957.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Neurology & Psychiatry American Medical Association

Dystonia Musculorum Deformans Alleviated by Chemopallidectomy and Chemopallidothalamectomy

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Publisher
American Medical Association
Copyright
Copyright © 1959 American Medical Association. All Rights Reserved.
ISSN
0096-6886
DOI
10.1001/archneurpsyc.1959.02340130025002
Publisher site
See Article on Publisher Site

Abstract

Abstract Of the many neurologic diseases which have failed to respond to medical or surgical therapeutic measures, the extrapyramidal disorders of childhood have, by and large, been considered as the most intractable, and have generally been regarded as hopeless. In 1951 Percival Bailey stated that "on the whole surgery has little application in the vast field of the extrapyramidal hyperkinesias." However, in the brief six years since this statement was made, considerable progress has been made as regards the possibilities for the surgical therapy of tremor and rigidity in the adult Parkinsonian patient. Our own series (St. Barnabas Hospital) of 800 cases of Parkinsonism treated by anterior choroidal artery occlusion (50 cases) and chemopallidectomy (750 cases) demonstrates that both tremor and rigidity can be alleviated without any neurologic sacrifice by the infliction of well-localized but sufficient-sized lesions in the globus pallidus and/or the ventrolateral nucleus of the thalamus. Similar progress has References 1. Deaver, G.: Cerebral Palsy: Methods of Evaluation and Treatment , Rehabilitation Monograph IX, New York, Institute of Physical Medicine and Rehabilitation, New York University-Bellevue Medical Center, 1955. 2. Parker, H. L.: Clinical Studies in Neurology , Springfield, Ill., Charles C Thomas, Publisher, 1956. 3. Meyers, R.: Surgical Experiments in Therapy of Certain "Extrapyramidal" Diseases: Current Evaluation , Acta psychiat. et neurol. , (Supp. 67) , pp. 3-42, 1951. 4. Meyers, R., in Clinical Neurology , edited by A. B. Baker, New York, Paul B. Hoeber, Inc., (medical book department of Harper & Brothers), 1955, Vol. 2, pp. 1107-1159. 5. Meyers, R.: Results of Bilateral Intermediate Midbrain Crusotomy in 7 Cases of Severe Athetotic and Dystonic Quadriparesis , Am. J. Phys. Med. 35: 84-105 ( (April) ) 1956. 6. Grinker, R. R., and Bucy, P. C.: Neurology , Ed. 4, Springfield, Ill., Charles C Thomas, Publisher, 1949. 7. Cooper, I. S.: Intracerebral Injection of Procaine into the Globus Pallidus in Hyperkinetic Disorders , Science 119:417-418 ( (March 26) ) 1954.Crossref 8. Cooper, I. S.: Chemopallidectomy: Investigative Technique in Geriatric Parkinsonians , Science 121:217-218 ( (Feb. 11) ) 1955.Crossref 9. Cooper, I. S.; Poloukhine, N., and Hoen, T. I.: Chemopallidectomy for Dystonia Musculorum Deformans , J. Am. Geriatrics Soc. 4:1208-1213 ( (Dec.) ) 1956. 10. Bravo, G., and Cooper, I. S.: Chemopallidectomy—Two Recent Technical Additions , J. Am. Geriatric Soc. 5:651-655 ( (July) ) 1957. 11. Gass, H.: Personal communication to the author. 12. Cooper, I. S.: Relief of Juveline Involuntary Movement Disorders by Chemopallidectomy , J. A. M. A. 164:1297-1301 ( (July 20) ) 1957.Crossref

Journal

A.M.A. Archives of Neurology & PsychiatryAmerican Medical Association

Published: Jan 1, 1959

References