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G. Brown, A. Rabson, D. Craig (1956)
Poliomyelitis vaccine studies.Public health reports, 71 6
Lossing Eh (1956)
Evaluation of Canadian poliomyelitis vaccination program, 1955.Canadian Journal of Public Health-revue Canadienne De Sante Publique, 47
G. Brown, D. Smith (1956)
Serologic response of infants and preschool children to poliomyelitis vaccine.Journal of the American Medical Association, 161 5
E. Lennette, N. Schmidt (1957)
Studies on the development and persistence of complement-fixing and neutralizing antibodies in human poliomyelitis.American journal of hygiene, 65 2
J. Salk (1955)
Vaccination against paralytic poliomyelitis performance and prospects.American journal of public health and the nation's health, 45 5 Pt 1
J. Salk (1956)
REQUIREMENTS FOR PERSISTENT IMMUNITY TO POLIOMYELITISThe American Journal of the Medical Sciences, 232
T. Francis (1957)
Evaluation of the 1954 field trial of poliomyelitis vaccine : final report
J. Melnick, Jr. Opton (1956)
Assay of poliomyelitis neutralizing antibody in disposable plastic panels.Bulletin of the World Health Organization, 14 1
A. Pope, R. Feemster, D. Rosengard, F. Hopkins, B. Vanadzin, E. Pattison (1956)
Evaluation of poliomyelitis vaccination in Massachusetts.The New England journal of medicine, 254 3
The persistence of the effects of immunization against poliomyelitis was studied in 139 children three years after primary inoculation and two years after booster inoculation with inactivated poliomyelitis vaccine. The criterion was the titer of neutralizing antibodies for the three immunological types of poliomyelitis virus, as measured colorimetrically by the protection of monkey-kidney cell suspensions from the metabolic inhibitory influence of the virus. School-age children who had received primary vaccination during the nationwide field trial of 1954 showed an average loss of only threefold to fourfold in antibody titer during the two-year period after secondary immunization and still had high levels indicative of protection. The levels of protection found appeared to be independent of the extent of primary stimulation. The younger children had markedly lower levels of antibody after the booster injection, but the mean loss of antibodies was of the same order of magnitude in the three groups. The degree of immunity and extent of loss during the two-year interval closely duplicated the values reported by others for patients convalescing from the disease itself.
JAMA – American Medical Association
Published: Apr 19, 1958
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