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Downbeat Nystagmus Associated With Dolichoectasia of the Vertebrobasilar Artery

Downbeat Nystagmus Associated With Dolichoectasia of the Vertebrobasilar Artery Abstract To the Editor. —It is with some interest that we read the article of Jacobson and Corbett.1 While there no doubt exist brain-stem disorders that can result in downbeat nystagmus as was emphasized in the article, it is of note that patient 3 of this article was receiving lithium. It is implied that, because the patient had not had lithium toxicity documented, this was not the cause of downbeat nystagmus. It has been noted, most recently in an article by Halmagyi et al,2 that with chronic lithium administration, toxicity is not necessary in order to develop irreversible downbeat nystagmus. I think it would be worthwhile to make this point clear in order to alert clinicians that patients with bipolar affective disorders, who are receiving therapeutic levels of lithium, may develop irreversible downbeat nystagmus despite decreasing or terminating lithium therapy. References 1. Jacobson DM, Corbett JJ. Downbeat nystagmus associated with dolichoectasia of the vertebrobasilar artery . Arch Neurol . 1989;16:1005-1008.Crossref 2. Halmagyi GM, Lessell I, Curthoys IS, Lessell S, Hoyt WF. Lithium-induced downbeat nystagmus . Am J Ophthalmol . 1989;107:664-670. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Downbeat Nystagmus Associated With Dolichoectasia of the Vertebrobasilar Artery

Archives of Neurology , Volume 47 (8) – Aug 1, 1990

Downbeat Nystagmus Associated With Dolichoectasia of the Vertebrobasilar Artery

Abstract

Abstract To the Editor. —It is with some interest that we read the article of Jacobson and Corbett.1 While there no doubt exist brain-stem disorders that can result in downbeat nystagmus as was emphasized in the article, it is of note that patient 3 of this article was receiving lithium. It is implied that, because the patient had not had lithium toxicity documented, this was not the cause of downbeat nystagmus. It has been noted, most recently in an article by Halmagyi et al,2 that...
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Publisher
American Medical Association
Copyright
Copyright © 1990 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1990.00530080025005
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor. —It is with some interest that we read the article of Jacobson and Corbett.1 While there no doubt exist brain-stem disorders that can result in downbeat nystagmus as was emphasized in the article, it is of note that patient 3 of this article was receiving lithium. It is implied that, because the patient had not had lithium toxicity documented, this was not the cause of downbeat nystagmus. It has been noted, most recently in an article by Halmagyi et al,2 that with chronic lithium administration, toxicity is not necessary in order to develop irreversible downbeat nystagmus. I think it would be worthwhile to make this point clear in order to alert clinicians that patients with bipolar affective disorders, who are receiving therapeutic levels of lithium, may develop irreversible downbeat nystagmus despite decreasing or terminating lithium therapy. References 1. Jacobson DM, Corbett JJ. Downbeat nystagmus associated with dolichoectasia of the vertebrobasilar artery . Arch Neurol . 1989;16:1005-1008.Crossref 2. Halmagyi GM, Lessell I, Curthoys IS, Lessell S, Hoyt WF. Lithium-induced downbeat nystagmus . Am J Ophthalmol . 1989;107:664-670.

Journal

Archives of NeurologyAmerican Medical Association

Published: Aug 1, 1990

References

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