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Abstract Background: Although panic disorder can be effectively alleviated by drug treatment, the relapse rate is high. By adding brief dynamic psychotherapy focused on the Psychosocial vulnerability of patients with panic disorder to an established drug treatment regimen, we hypothesized that this would result in a lower relapse rate after pharmacotherapy. Methods: Patients with panic disorder (defined by DSM-III-R) were randomized to treatment with either clomipramine for 9 months (n=20), or clomipramine for 9 months combined with 15 weekly sessions of brief dynamic psychotherapy (n=20). Measures of anxiety and depression were collected at intake and at regular intervals. The patients had blind follow-up interviews at 6, 12, and 18 months after beginning treatment. Results: All patients in both groups became free of panic attacks within 26 weeks of the start of treatment. 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Archives of General Psychiatry – American Medical Association
Published: Aug 1, 1996
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