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DIURETIC ACTION OF INTRAVENOUS SODIUM DEHYDROCHOLATE

DIURETIC ACTION OF INTRAVENOUS SODIUM DEHYDROCHOLATE Diuresis is obtained in therapeutics by the use of various substances acting through different mechanisms and belonging to different groups. According to their chemical structure and their pharmacologic action, diuretics may be classified as follows: water, the saline diuretics, the xanthines (caffeine, theobromine and theophylline), the digitalis group, mercurial diuretics and finally liver and bile acids. In the healthy individual with normal water balance, water acts as a diuretic when it is ingested without sodium chloride. Therapeutically this finds use in the restriction of salt intake in the presence of edema, so that water and sodium chloride are eliminated. The saline diuretics potassium and ammonium salts and urea induce diuresis probably through their osmotic effect. Ingested by mouth, they are most frequently used in conjunction with digitalis or to dilute the urine and decrease its acidity in genito-urinary irritations. Used in large quantities to produce marked diuresis, they cause gastro-intestinal http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

DIURETIC ACTION OF INTRAVENOUS SODIUM DEHYDROCHOLATE

WEIGAND, FRANKLIN A.
JAMA , Volume 105 (25) – Dec 21, 1935
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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1935 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1935.02760510006002
Publisher site
See Article on Publisher Site

Abstract

Diuresis is obtained in therapeutics by the use of various substances acting through different mechanisms and belonging to different groups. According to their chemical structure and their pharmacologic action, diuretics may be classified as follows: water, the saline diuretics, the xanthines (caffeine, theobromine and theophylline), the digitalis group, mercurial diuretics and finally liver and bile acids. In the healthy individual with normal water balance, water acts as a diuretic when it is ingested without sodium chloride. Therapeutically this finds use in the restriction of salt intake in the presence of edema, so that water and sodium chloride are eliminated. The saline diuretics potassium and ammonium salts and urea induce diuresis probably through their osmotic effect. Ingested by mouth, they are most frequently used in conjunction with digitalis or to dilute the urine and decrease its acidity in genito-urinary irritations. Used in large quantities to produce marked diuresis, they cause gastro-intestinal

Journal

JAMA – American Medical Association

Published: Dec 21, 1935

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