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DISTURBANCE OF GASTRO-INTESTINAL INNERVATION IN POLIOMYELITIS

DISTURBANCE OF GASTRO-INTESTINAL INNERVATION IN POLIOMYELITIS Typhoid fever may sometimes cause paralysis of the muscles of the thigh, probably as a result of the spread of the typhoid toxins from the intestine along the sympathetic to the somatic nerves.1 Natural protection is such that only patients who are extremely ill with the disease have muscular weakness, an extraordinary fact when one considers the amount of toxic material contained in the intestines of these patients. Since toxins from colon bacilli are considered to be much less potent for the human being than are those from Bacillus typhosus, one does not expect that the toxins from the colon bacilli will spread along the afferent or efferent sympathetic fibers and cause local paralysis by involvement of the somatic nerves. The validity of this assumption was proved by the fact that the injection of enteric toxins into the subserosa or into the lumen of the small intestine of Macacus http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

DISTURBANCE OF GASTRO-INTESTINAL INNERVATION IN POLIOMYELITIS

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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1936 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1936.04140030049004
Publisher site
See Article on Publisher Site

Abstract

Typhoid fever may sometimes cause paralysis of the muscles of the thigh, probably as a result of the spread of the typhoid toxins from the intestine along the sympathetic to the somatic nerves.1 Natural protection is such that only patients who are extremely ill with the disease have muscular weakness, an extraordinary fact when one considers the amount of toxic material contained in the intestines of these patients. Since toxins from colon bacilli are considered to be much less potent for the human being than are those from Bacillus typhosus, one does not expect that the toxins from the colon bacilli will spread along the afferent or efferent sympathetic fibers and cause local paralysis by involvement of the somatic nerves. The validity of this assumption was proved by the fact that the injection of enteric toxins into the subserosa or into the lumen of the small intestine of Macacus

Journal

American journal of diseases of children – American Medical Association

Published: Sep 1, 1936

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