Abstract Introduction The surgical pendulum is swinging toward universal adoption of the recent more conservative type surgical procedures which have been developed in a number of surgical centers during the past 20 years. As a result of the findings of several investigators, particularly the monumental work of Dragstedt and associates, the basic altered gastric physiology in the pathogenesis of duodenal ulcer is now known and understood. By the clinical application of these basic physiologic principles, several surgeons have patterned conservative surgical procedures to control duodenal ulcer without affecting, to any serious degree, the normal gastric functions or nutritional status of the patients. In addition, several of these procedures have reduced the incidence and severity of many of the undesirable postoperative sequelae associated with many of the older and time-tested surgical procedures for this chronic disease.It has been definitely established by careful research studies that there are two major physiologic phases References 1. Palumbo, L. T.; Sharpe, W. S.; Lulu, D. J.; Vespa, R.; and Colon-Bonet, J.: Antrectomy With Vagectomy for Chronic Duodenal Ulcer , Surgery 46:1005 ( (Dec) ) 1959. 2. Palumbo, L. T.; Sharpe, W. S.; Lulu, D. J.; Vespa, R.; and Colon-Bonet, J.: Antrectomy With Vagectomy or Partial Gastrectomy for Chronic Duodenal Ulcer: A Comparative Analysis , Surg Clin N Amer 39:1697 ( (Dec) ) 1959. 3. Palumbo, L. T.; Sharpe, W. S.; Lulu, D. J.; and Vespa, R.: Antrectomy With Bilateral Vagectomy for Chronic Duodenal Ulcer, Scientific Exhibit , Postgrad Med 30:591 ( (Dec) ) 1961. 4. Palumbo, L. T.; Sharpe, W. S.; Lulu, D. J.; Bloom, M. H.; and Porter, H. R.: Results in 300 Cases of Antrectomy With Bilateral Vagectomy for Chronic Duodenal Ulcer , Surgery 51:289 ( (March) ) 1962. 5. Palumbo, L. T., and Sharpe, W. S.: Antrectomy With Vagectomy for Chronic Duodenal Ulcer , Clin Med 69:1131 ( (May) ) 1962. 6. Dragstedt, L. R.: The Etiology of Gastric and Duodenal Ulcers , Postgrad Med 15:99, 1954. 7. Dragstedt, L. R.: Physiology of Gastric Antrum , AMA Arch Surg 75:552, 1957.Crossref 8. Dragstedt, L. R.; Oberhelman, H. A., Jr.; Zubiran, J. M.; and Woodward, E. R.: Antrum Motility as a Stimulus for Gastric Secretion , Gastroenterology 24:71, 1953.
Archives of Surgery – American Medical Association
Published: Dec 1, 1963
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