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Disposable Bubble Oxygenator: Experimental Studies of Its Performance

Disposable Bubble Oxygenator: Experimental Studies of Its Performance Abstract AN EVALUATION of the disposable bubble oxygenator (Travenol U-310) has been done under controlled conditions to determine the circumstances under which optimum performance might be expected and to define the margin of safety which this oxygenator affords. Blood of any desired gas composition was obtained by recirculation through a stationary screen oxygenator (Mayo-Gibbon) using various gas mixtures in the chamber. The blood was then passed a single time through the bubble oxygenator and changes in a particular parameter measured. Three parameters have been studied: (1) the effect of varying the gas flow rate to the oxygenator, (2) the effect of blood flow on the ability of the oxygenator to oxygenate blood, and (3) the ability of the oxygenator to remove carbon dioxide. Experimental Design Preliminary to the experimental determination, it was necessary to have information on the efficiency of the screen (control) oxygenator. In these experiments efficiency was defined in References 1. Montgomery, V.: Respiratory Characteristics of Extracorporeal Pump Oxygenators , J Thorac Cardiov Surg 39:288, 1960. 2. Theye, R.A.; Kirklin, J.W.; and Fowler, W.S.: Performance and Film Volume of Sheet and Screen Vertical-Film Oxygenators , J Thorac Cardiov Surg 43:481, 1962. 3. Severinghaus, J.W.: Oxyhemoglobin Dissociation Curve Correction for Temperature and pH Variation in Human Blood , J Appl Physiol 12:485, 1958. 4. Burbank, A.; Ferguson, T.B.; and Burford, T.H.: Carbon Dioxide Flooding of the Chest in Open Heart Surgery , J Thorac Cardiov Surg 50: 691, 1965. 5. Cooley, D.A.; Beall, A.C., Jr.; and Grondin, D.: Open-Heart Operations With Disposable Oxygenators, 5% Dextrose Prime, and Normothermia , Surgery 52:713, 1962. 6. Just, J., et al: A Simplified Method for Pulmonary Artery By-Pass , J Thorac Cardiov Surg 48:807, 1964. 7. Roe, B.B., et al: Total Body Perfusion in Cardiac Operations , Arch Surg 88:128, 1964.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Disposable Bubble Oxygenator: Experimental Studies of Its Performance

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Publisher
American Medical Association
Copyright
Copyright © 1966 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1966.01330040124024
Publisher site
See Article on Publisher Site

Abstract

Abstract AN EVALUATION of the disposable bubble oxygenator (Travenol U-310) has been done under controlled conditions to determine the circumstances under which optimum performance might be expected and to define the margin of safety which this oxygenator affords. Blood of any desired gas composition was obtained by recirculation through a stationary screen oxygenator (Mayo-Gibbon) using various gas mixtures in the chamber. The blood was then passed a single time through the bubble oxygenator and changes in a particular parameter measured. Three parameters have been studied: (1) the effect of varying the gas flow rate to the oxygenator, (2) the effect of blood flow on the ability of the oxygenator to oxygenate blood, and (3) the ability of the oxygenator to remove carbon dioxide. Experimental Design Preliminary to the experimental determination, it was necessary to have information on the efficiency of the screen (control) oxygenator. In these experiments efficiency was defined in References 1. Montgomery, V.: Respiratory Characteristics of Extracorporeal Pump Oxygenators , J Thorac Cardiov Surg 39:288, 1960. 2. Theye, R.A.; Kirklin, J.W.; and Fowler, W.S.: Performance and Film Volume of Sheet and Screen Vertical-Film Oxygenators , J Thorac Cardiov Surg 43:481, 1962. 3. Severinghaus, J.W.: Oxyhemoglobin Dissociation Curve Correction for Temperature and pH Variation in Human Blood , J Appl Physiol 12:485, 1958. 4. Burbank, A.; Ferguson, T.B.; and Burford, T.H.: Carbon Dioxide Flooding of the Chest in Open Heart Surgery , J Thorac Cardiov Surg 50: 691, 1965. 5. Cooley, D.A.; Beall, A.C., Jr.; and Grondin, D.: Open-Heart Operations With Disposable Oxygenators, 5% Dextrose Prime, and Normothermia , Surgery 52:713, 1962. 6. Just, J., et al: A Simplified Method for Pulmonary Artery By-Pass , J Thorac Cardiov Surg 48:807, 1964. 7. Roe, B.B., et al: Total Body Perfusion in Cardiac Operations , Arch Surg 88:128, 1964.Crossref

Journal

Archives of SurgeryAmerican Medical Association

Published: Oct 1, 1966

References