Abstract To the Editor.— The treatment of papular mucinosis is usually unsatisfactory, but we describe here a patient with discrete papular mucinosis whose lesions responded to therapy with intralesional and topical steroids. Report of a Case.— A 32-year-old man presented with multiple discrete nodules over his limbs and chest. The patient reported that he had these nodules for 4 years. The lesions had appeared within a few months and then remained unchanged.Findings from his physical examination revealed numerous skincolored papules, mainly over the upper limbs (Fig 1), with one or two lesions over the back and legs.A skin biopsy specimen of one papule from the arm showed a loose, irregular proliferation of spindle cells in the dermis, in places following a storiform pattern (Fig 2). Irregular bundles of collagen and a moderate perivascular infiltrate, consisting mostly of plasma cells, were seen. Sections of the papular lesion were stained with References 1. Montgomery H, Underwood LJ. Lichen myxedematosus (differentiation from cutaneous myxedema or mucoid states) . J Invest Dermatol. 1953;20:213-236. 2. Rongioletti F, Rebora A, Crovato F. Acral persistent papular mucinosis: a new entity? Arch Dermatol. 1986;122:1237-1239.Crossref 3. Rongioletti F, Rebora A. The new cutaneous mucinoses: a review with an up-to-date classification of cutaneous mucinoses . J Am Acad Dermatol. 1991; 24:265-270.Crossref 4. Cosky RJ, Mehregan A. Papular mucinosis . Int J Dermatol. 1977;16:741-744.Crossref 5. Truhan AP, Roenigk HH Jr. The cutaneous mucinoses . J Am Acad Dermatol. 1986;14:1-18.Crossref 6. Feldman P, Shapiro L, Pick AI, et al. Scleromyxedema: a dramatic response to melphalan . Arch Dermatol. 1969;99:51-56.Crossref 7. Harris RB, Perry HO, Kyle RA, et al. Treatment of scleromyxedema with melphalan . Arch Dermatol. 1979;115:295-299.Crossref 8. Howsden SM, Herndon JH, Freeman RG. Lichen myxedematosus: a dermal infiltrative disorder responsive to cyclophosphamide therapy . Arch Dermatol. 1975;111:1325-1330.Crossref 9. Jessen RT, Strait M, Becker LE. Lichen myxedematosus: treatment with cyclophosphamide . Int J Dermatol. 1978;17:733-839. 10. Naeyaert JM. Papular mucinosis . Dermatologica . 1985;171:508.
Archives of Dermatology – American Medical Association
Published: Jun 1, 1992
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera