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Direct to Angiography Suite Without Stopping for Computed Tomography Imaging for Patients With Acute Stroke

Direct to Angiography Suite Without Stopping for Computed Tomography Imaging for Patients With... Key PointsQuestionDoes direct transfer to angiography suite (DTAS) improve functional outcomes compared with usual imaging workflow for patients within 6 hours of onset of symptoms for large vessel occlusion ischemic stroke? FindingsIn this randomized clinical trial including 174 patients with suspected large vessel occlusion stroke on admission, large vessel occlusion was confirmed in 147. The use of a DTAS protocol improved in-hospital workflow times, increased the rate of endovascular treatment, and decreased the severity of disability across the range of modified Rankin Scale scores. MeaningFor patients with acute ischemic stroke due to large vessel occlusion within 6 hours of symptom onset, compared with usual imaging, the use of DTAS led to safe patient triage for acute stroke endovascular treatment, decreased workflow times, and improved outcomes; ongoing international, multicenter clinical trials are exploring the generalizability of these results. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2021 American Medical Association. All Rights Reserved.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/jamaneurol.2021.2385
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionDoes direct transfer to angiography suite (DTAS) improve functional outcomes compared with usual imaging workflow for patients within 6 hours of onset of symptoms for large vessel occlusion ischemic stroke? FindingsIn this randomized clinical trial including 174 patients with suspected large vessel occlusion stroke on admission, large vessel occlusion was confirmed in 147. The use of a DTAS protocol improved in-hospital workflow times, increased the rate of endovascular treatment, and decreased the severity of disability across the range of modified Rankin Scale scores. MeaningFor patients with acute ischemic stroke due to large vessel occlusion within 6 hours of symptom onset, compared with usual imaging, the use of DTAS led to safe patient triage for acute stroke endovascular treatment, decreased workflow times, and improved outcomes; ongoing international, multicenter clinical trials are exploring the generalizability of these results.

Journal

JAMA NeurologyAmerican Medical Association

Published: Sep 2, 2021

References