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Direct Serum Bilirubin and the Sulfobromophthalein Test in Occult Liver Disease

Direct Serum Bilirubin and the Sulfobromophthalein Test in Occult Liver Disease When a sensitive method for measuring direct serum bilirubin (DB) was used, a third of the patients with liver or biliary tract disease had elevated DB levels, but normal levels of total serum bilirubin (TB). The correlation of DB and sulfobromophthalein (BSP) retention was studied because DB and BSP are cleared through the same hepatic pathway. Our findings support the clinical and chemical validity of DB measurements as an index of occult liver disease. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Direct Serum Bilirubin and the Sulfobromophthalein Test in Occult Liver Disease

JAMA , Volume 201 (13) – Sep 25, 1967

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Publisher
American Medical Association
Copyright
Copyright © 1967 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1967.03130130073022
Publisher site
See Article on Publisher Site

Abstract

When a sensitive method for measuring direct serum bilirubin (DB) was used, a third of the patients with liver or biliary tract disease had elevated DB levels, but normal levels of total serum bilirubin (TB). The correlation of DB and sulfobromophthalein (BSP) retention was studied because DB and BSP are cleared through the same hepatic pathway. Our findings support the clinical and chemical validity of DB measurements as an index of occult liver disease.

Journal

JAMAAmerican Medical Association

Published: Sep 25, 1967

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