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DIGITALIS STUDIES ON CHILDREN WITH HEART DISEASE

DIGITALIS STUDIES ON CHILDREN WITH HEART DISEASE It is generally agreed that digitalis finds its greatest use and value in its slowing of the ventricular rate during established auricular fibrillation. That digitalis may, however, initiate and be responsible for the development of this arrhythmia in children with heart disease has been questioned on the ground that other factors responsible for the onset of this irregularity could not be ruled out.1 Since the rational use of digitalis depends in a great measure on a recognition and appreciation of its toxic manifestations, I have considered it worth while to call particular attention to the fact that digitalis in adequate doses can produce both the transient and the permanent forms of auricular fibrillation in children with heart disease. Moreover, the development of this arrhythmia is an early toxic manifestation during the course of digitalis therapy, and in some instances may result fatally. The close relationship of administration of digitalis http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

DIGITALIS STUDIES ON CHILDREN WITH HEART DISEASE

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Publisher
American Medical Association
Copyright
Copyright © 1930 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1930.01930150081010
Publisher site
See Article on Publisher Site

Abstract

It is generally agreed that digitalis finds its greatest use and value in its slowing of the ventricular rate during established auricular fibrillation. That digitalis may, however, initiate and be responsible for the development of this arrhythmia in children with heart disease has been questioned on the ground that other factors responsible for the onset of this irregularity could not be ruled out.1 Since the rational use of digitalis depends in a great measure on a recognition and appreciation of its toxic manifestations, I have considered it worth while to call particular attention to the fact that digitalis in adequate doses can produce both the transient and the permanent forms of auricular fibrillation in children with heart disease. Moreover, the development of this arrhythmia is an early toxic manifestation during the course of digitalis therapy, and in some instances may result fatally. The close relationship of administration of digitalis

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Mar 1, 1930

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