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Differential Renal Function Studies in Segmental Renal Ischemia

Differential Renal Function Studies in Segmental Renal Ischemia Five of 11 patients with hypertension secondary to surgically confirmed segmental renal ischemia had less than a 2:1 difference in urine flow rates between the two kidneys; significant lesions were present with as little as 11% increase in inulin concentrations. In addition, branch arterial stenosis may be so severe that no glomerular filtrate is produced by the ischemic segment of the kidney. In these cases the disparity in "renal mass vs renal water" may be the only abnormality seen on split function study. These findings suggest that some patients may have curable hypertension secondary to segmental renal artery disease involving such a small area of the kidney that strict adherence to previous criteria for a positive function study may be misleading. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Differential Renal Function Studies in Segmental Renal Ischemia

JAMA , Volume 217 (6) – Aug 9, 1971

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References (7)

Publisher
American Medical Association
Copyright
Copyright © 1971 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1971.03190060030008
Publisher site
See Article on Publisher Site

Abstract

Five of 11 patients with hypertension secondary to surgically confirmed segmental renal ischemia had less than a 2:1 difference in urine flow rates between the two kidneys; significant lesions were present with as little as 11% increase in inulin concentrations. In addition, branch arterial stenosis may be so severe that no glomerular filtrate is produced by the ischemic segment of the kidney. In these cases the disparity in "renal mass vs renal water" may be the only abnormality seen on split function study. These findings suggest that some patients may have curable hypertension secondary to segmental renal artery disease involving such a small area of the kidney that strict adherence to previous criteria for a positive function study may be misleading.

Journal

JAMAAmerican Medical Association

Published: Aug 9, 1971

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