Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Dietary and Supplemental Calcium Intake and Mortality

Dietary and Supplemental Calcium Intake and Mortality Letters COMMENT & RESPONSE To the Editor Several recent articles documented increased car- diovascular mortality associated with high calcium intake, in Dietary and Supplemental Calcium Intake particular supplemental calcium. Most epidemiological stud- and Mortality ies of calcium intake and cardiovascular health have been con- ducted in white individuals with moderate to high calcium in- To the Editor The study by Xiao et al demonstrating increased take. Only a few specifically focused on cardiovascular cardiovascular risk from dietary calcium supplementation mortality. Xiao et al reported that supplemental calcium was highlights an important but underappreciated principle: the associated with elevated cardiovascular disease (CVD) mor- nontransitivity of clinical inference. In formal logic, if A im- tality in men but not in women, whereas dietary calcium in- plies B and B implies C, then it follows that A implies C. How- take was unrelated to CVD death in either sex. In contrast, an- ever, if calcium deficiency is associated with poor health out- other female cohort study showed that dietary calcium intake comes and calcium supplementation can raise calcium levels, above 1400 mg/d was associated with higher all-cause and CVD it does not necessarily follow that taking calcium supple- mortality compared with lower http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

Dietary and Supplemental Calcium Intake and Mortality

Download PDF
3 pages

Loading next page...
 
/lp/american-medical-association/dietary-and-supplemental-calcium-intake-and-mortality-0QeU4BLcOO

References (5)

Publisher
American Medical Association
Copyright
Copyright 2013 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/jamainternmed.2013.9260
pmid
24165842
Publisher site
See Article on Publisher Site

Abstract

Letters COMMENT & RESPONSE To the Editor Several recent articles documented increased car- diovascular mortality associated with high calcium intake, in Dietary and Supplemental Calcium Intake particular supplemental calcium. Most epidemiological stud- and Mortality ies of calcium intake and cardiovascular health have been con- ducted in white individuals with moderate to high calcium in- To the Editor The study by Xiao et al demonstrating increased take. Only a few specifically focused on cardiovascular cardiovascular risk from dietary calcium supplementation mortality. Xiao et al reported that supplemental calcium was highlights an important but underappreciated principle: the associated with elevated cardiovascular disease (CVD) mor- nontransitivity of clinical inference. In formal logic, if A im- tality in men but not in women, whereas dietary calcium in- plies B and B implies C, then it follows that A implies C. How- take was unrelated to CVD death in either sex. In contrast, an- ever, if calcium deficiency is associated with poor health out- other female cohort study showed that dietary calcium intake comes and calcium supplementation can raise calcium levels, above 1400 mg/d was associated with higher all-cause and CVD it does not necessarily follow that taking calcium supple- mortality compared with lower

Journal

JAMA Internal Medicine – American Medical Association

Published: Oct 28, 2013

There are no references for this article.