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Diagnostic Criteria and Phenotypes of Pemphigoid and the Association With Gliptins

Diagnostic Criteria and Phenotypes of Pemphigoid and the Association With Gliptins Opinion EDITORIAL Diagnostic Criteria and Phenotypes of Pemphigoid and the Association With Gliptins Asli Bilgic Temel, MD; Dedee F. Murrell, MA, BMBCh, MD, FACD, FRCP In this issue, there are 2 excellent large retrospective studies study found that 17% of the cohort had mucosal lesions, with almost 31% having 2 mucosal surfaces involved con- from single centers in Groningen, The Netherlands, and Haifa, Israel of patients referred for possible bullous pemphi- comitantly and almost 5% with disease involving the larynx. goid (BP). In addition, there Typically, younger patients with more extensive disease that is a nationwide population- included the head and neck had mucosal involvement; they based study from Korea also had a significantly elevated erythrocyte sedimentation Related articles pages 158, 166, and 172 evaluating the risk of BP rate (ESR), and not surprisingly, required more aggressive in patients with diabetes treatment. The main limitation of the study was that disease receiving dipeptidyl peptidase 4 inhibitors (gliptins). severity was not validated with the Bullous Pemphigoid 1 5 The aim of the Dutch study by Meijer et al was to deter- Disease Area Index. In a recent study of pemphigus mine the minimum diagnostic criteria for pemphigoid, which vulgaris, the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Dermatology American Medical Association

Diagnostic Criteria and Phenotypes of Pemphigoid and the Association With Gliptins

JAMA Dermatology , Volume 155 (2) – Feb 9, 2019

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Publisher
American Medical Association
Copyright
Copyright 2019 American Medical Association. All Rights Reserved.
ISSN
2168-6068
eISSN
2168-6084
DOI
10.1001/jamadermatol.2018.4847
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL Diagnostic Criteria and Phenotypes of Pemphigoid and the Association With Gliptins Asli Bilgic Temel, MD; Dedee F. Murrell, MA, BMBCh, MD, FACD, FRCP In this issue, there are 2 excellent large retrospective studies study found that 17% of the cohort had mucosal lesions, with almost 31% having 2 mucosal surfaces involved con- from single centers in Groningen, The Netherlands, and Haifa, Israel of patients referred for possible bullous pemphi- comitantly and almost 5% with disease involving the larynx. goid (BP). In addition, there Typically, younger patients with more extensive disease that is a nationwide population- included the head and neck had mucosal involvement; they based study from Korea also had a significantly elevated erythrocyte sedimentation Related articles pages 158, 166, and 172 evaluating the risk of BP rate (ESR), and not surprisingly, required more aggressive in patients with diabetes treatment. The main limitation of the study was that disease receiving dipeptidyl peptidase 4 inhibitors (gliptins). severity was not validated with the Bullous Pemphigoid 1 5 The aim of the Dutch study by Meijer et al was to deter- Disease Area Index. In a recent study of pemphigus mine the minimum diagnostic criteria for pemphigoid, which vulgaris, the

Journal

JAMA DermatologyAmerican Medical Association

Published: Feb 9, 2019

References