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Diagnosis and Treatment of Mycosis Fungoides-Reply

Diagnosis and Treatment of Mycosis Fungoides-Reply This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.— It has long been acknowledged that pretumorous lesions of mycosis fungoides, such as parapsoriasis en plaques and poikiloderma vasculare atrophicans, cannot always be diagnosed with certainty as mycosis fungoides, clinically or histologically. Our paper titled "Spongiotic Simulants of Mycosis Fungoides" told of another unsettling phenomenon, namely, of patients who did not have mycosis fungoides, but whose skin biopsy specimens showed spongiotic foci containing atypical mononuclear cells that were indistinguishable from Pautrier microabscesses. A corollary from this finding was that patients who do not have absolutely proven mycosis fungoides should not be treated with potentially harmful modalities. If the electron beam or topical mechlorethamine hydrochloride therapy, advocated by Drs. Constantine and Fuks for "early cases of mycosis fungoides," had been given to our patients with spongiotic simulants of mycosis fungoides, the lesions would have likely gone into complete remission, but at what a price! Our patients, in fact, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Diagnosis and Treatment of Mycosis Fungoides-Reply

Archives of Dermatology , Volume 110 (2) – Aug 1, 1974

Diagnosis and Treatment of Mycosis Fungoides-Reply

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.— It has long been acknowledged that pretumorous lesions of mycosis fungoides, such as parapsoriasis en plaques and poikiloderma vasculare atrophicans, cannot always be diagnosed with certainty as mycosis fungoides, clinically or histologically. Our paper titled "Spongiotic Simulants of Mycosis Fungoides" told of another...
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Publisher
American Medical Association
Copyright
Copyright © 1974 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1974.01630080090046
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.— It has long been acknowledged that pretumorous lesions of mycosis fungoides, such as parapsoriasis en plaques and poikiloderma vasculare atrophicans, cannot always be diagnosed with certainty as mycosis fungoides, clinically or histologically. Our paper titled "Spongiotic Simulants of Mycosis Fungoides" told of another unsettling phenomenon, namely, of patients who did not have mycosis fungoides, but whose skin biopsy specimens showed spongiotic foci containing atypical mononuclear cells that were indistinguishable from Pautrier microabscesses. A corollary from this finding was that patients who do not have absolutely proven mycosis fungoides should not be treated with potentially harmful modalities. If the electron beam or topical mechlorethamine hydrochloride therapy, advocated by Drs. Constantine and Fuks for "early cases of mycosis fungoides," had been given to our patients with spongiotic simulants of mycosis fungoides, the lesions would have likely gone into complete remission, but at what a price! Our patients, in fact,

Journal

Archives of DermatologyAmerican Medical Association

Published: Aug 1, 1974

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