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Diagnosing Encephalitis, Not Otherwise Specified

Diagnosing Encephalitis, Not Otherwise Specified Letters text in which the brain biopsy was obtained is of limited value Diagnosing Encephalitis, and would contribute little to either reaching a more specific Not Otherwise Specified diagnosis or affecting management decision making. To the Editor We read with interest an article published by Gelfand et al. The authors presented their institutional Zhi-li Wang, MD series of 49 patients who were given the initial diagnosis of Eric Lancaster, MD, PhD encephalitis, not otherwise specified (ENOS) on pathologic Li Yang, MD, PhD review. For the 29 patients whose original pathologic mate- rial was available for review, subsequent neuropathologic Author Affiliations: Department of Neurology, The Second Xiangya Hospital, review led to a more specific categorization in 34%. Among Central South University, Hunan, China (Wang, Yang); Department of the 19 patients who still had ENOS after additional neuro- Neurology, Hospital of the University of Pennsylvania, Philadelphia (Lancaster). pathologic review, a definite diagnosis was reached in 32% Corresponding Author: Li Yang, MD, PhD, Department of Neurology, The based on ancillary testing, subsequent clinical information, Second Xiangya Hospital of Central South University, 139 Renmin Middle Rd, Changsha, Hunan, China, 410011 (yangli762@gmail.com). and clinical follow-up. The authors concluded that it may Conflict of Interest http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

Diagnosing Encephalitis, Not Otherwise Specified

JAMA Neurology , Volume 72 (6) – Jun 1, 2015

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Publisher
American Medical Association
Copyright
Copyright 2015 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/jamaneurol.2015.0542
pmid
26053445
Publisher site
See Article on Publisher Site

Abstract

Letters text in which the brain biopsy was obtained is of limited value Diagnosing Encephalitis, and would contribute little to either reaching a more specific Not Otherwise Specified diagnosis or affecting management decision making. To the Editor We read with interest an article published by Gelfand et al. The authors presented their institutional Zhi-li Wang, MD series of 49 patients who were given the initial diagnosis of Eric Lancaster, MD, PhD encephalitis, not otherwise specified (ENOS) on pathologic Li Yang, MD, PhD review. For the 29 patients whose original pathologic mate- rial was available for review, subsequent neuropathologic Author Affiliations: Department of Neurology, The Second Xiangya Hospital, review led to a more specific categorization in 34%. Among Central South University, Hunan, China (Wang, Yang); Department of the 19 patients who still had ENOS after additional neuro- Neurology, Hospital of the University of Pennsylvania, Philadelphia (Lancaster). pathologic review, a definite diagnosis was reached in 32% Corresponding Author: Li Yang, MD, PhD, Department of Neurology, The based on ancillary testing, subsequent clinical information, Second Xiangya Hospital of Central South University, 139 Renmin Middle Rd, Changsha, Hunan, China, 410011 (yangli762@gmail.com). and clinical follow-up. The authors concluded that it may Conflict of Interest

Journal

JAMA NeurologyAmerican Medical Association

Published: Jun 1, 2015

References