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M. Gable, Heather Sheriff, J. Dalmau, D. Tilley, C. Glaser (2012)
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Letters text in which the brain biopsy was obtained is of limited value Diagnosing Encephalitis, and would contribute little to either reaching a more specific Not Otherwise Specified diagnosis or affecting management decision making. To the Editor We read with interest an article published by Gelfand et al. The authors presented their institutional Zhi-li Wang, MD series of 49 patients who were given the initial diagnosis of Eric Lancaster, MD, PhD encephalitis, not otherwise specified (ENOS) on pathologic Li Yang, MD, PhD review. For the 29 patients whose original pathologic mate- rial was available for review, subsequent neuropathologic Author Affiliations: Department of Neurology, The Second Xiangya Hospital, review led to a more specific categorization in 34%. Among Central South University, Hunan, China (Wang, Yang); Department of the 19 patients who still had ENOS after additional neuro- Neurology, Hospital of the University of Pennsylvania, Philadelphia (Lancaster). pathologic review, a definite diagnosis was reached in 32% Corresponding Author: Li Yang, MD, PhD, Department of Neurology, The based on ancillary testing, subsequent clinical information, Second Xiangya Hospital of Central South University, 139 Renmin Middle Rd, Changsha, Hunan, China, 410011 (yangli762@gmail.com). and clinical follow-up. The authors concluded that it may Conflict of Interest
JAMA Neurology – American Medical Association
Published: Jun 1, 2015
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