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Diagnosing Childhood Tuberculosis

Diagnosing Childhood Tuberculosis Opinion EDITORIAL A Small Step Forward Jeffrey R. Starke, MD; Andrea T. Cruz, MD Prior to 2012, there were no reliable estimates of the inci- gastric aspirate and sputum induction, for detecting the organ- dence of tuberculosis in the world’s children. Using the only ism in children younger than 5 years in whom tuberculosis dis- ease was suspected because of symptoms and an abnormal chest available information, in 2013, the World Health Organiza- tion estimated there were approximately 500 000 annual cases radiograph result. In this cross-sectional study, the authors re- and 89 000 deaths among cruited almost 300 children in Kenya from inpatient and out- children not living with HIV; patient settings experiencing persistent cough, fever, or mal- Related article there were no data to even es- nutrition who also had a lung parenchymal abnormality on chest timate the mortality among children living with HIV. Through- radiography or persistent cervical adenopathy and had not re- out the next several years, modeling studies suggested that the sponded to treatment of other infections. Up to 2 samples each rates of cases and mortality were much higher. Using these of gastric aspirates, induced sputa, nasopharyngeal aspirates, techniques, in 2019, the World http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Pediatrics American Medical Association

Diagnosing Childhood Tuberculosis

Starke, Jeffrey R.; Cruz, Andrea T.
JAMA Pediatrics , Volume 175 (5) – May 22, 2021
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References (11)

Publisher
American Medical Association
Copyright
Copyright 2021 American Medical Association. All Rights Reserved.
ISSN
2168-6203
eISSN
2168-6211
DOI
10.1001/jamapediatrics.2020.6078
Publisher site
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Abstract

Opinion EDITORIAL A Small Step Forward Jeffrey R. Starke, MD; Andrea T. Cruz, MD Prior to 2012, there were no reliable estimates of the inci- gastric aspirate and sputum induction, for detecting the organ- dence of tuberculosis in the world’s children. Using the only ism in children younger than 5 years in whom tuberculosis dis- ease was suspected because of symptoms and an abnormal chest available information, in 2013, the World Health Organiza- tion estimated there were approximately 500 000 annual cases radiograph result. In this cross-sectional study, the authors re- and 89 000 deaths among cruited almost 300 children in Kenya from inpatient and out- children not living with HIV; patient settings experiencing persistent cough, fever, or mal- Related article there were no data to even es- nutrition who also had a lung parenchymal abnormality on chest timate the mortality among children living with HIV. Through- radiography or persistent cervical adenopathy and had not re- out the next several years, modeling studies suggested that the sponded to treatment of other infections. Up to 2 samples each rates of cases and mortality were much higher. Using these of gastric aspirates, induced sputa, nasopharyngeal aspirates, techniques, in 2019, the World

Journal

JAMA Pediatrics – American Medical Association

Published: May 22, 2021

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