Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

DIABETES INSIPIDUS

DIABETES INSIPIDUS No fundamental change in the symptomatic treatment of diabetes insipidus has occurred since 1913, when von der Velden1 in Germany and Farini and Ceccaroni2 in Italy, working independently, discovered the prompt, almost specific though temporary, control of excessive thirst and polyuria in patients suffering from diabetes insipidus following subcutaneous injections of extracts from the posterior lobe of the pituitary gland. Although the rôle of the posterior lobe in regulating normal water metabolism is still obscure, its antidiuretic effect with the adjustment of water balance and the correction of dehydration in diabetes insipidus has been abundantly confirmed.3 In seeking to remove the necessity for daily, painful hypodermic injections, attempts have been made to obtain the specific effect of the posterior lobe by the enteral administration of extracts4 and of fresh glands.5 All have proved totally ineffective or so variable in their action as to be impracticable. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

DIABETES INSIPIDUS

SMITH, FRANCIS M.
JAMA , Volume 102 (9) – Mar 3, 1934
Download PDF
5 pages

Loading next page...
 
/lp/american-medical-association/diabetes-insipidus-Vn18UYUxAJ

References (6)

Publisher
American Medical Association
Copyright
Copyright © 1934 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1934.02750090006003
Publisher site
See Article on Publisher Site

Abstract

No fundamental change in the symptomatic treatment of diabetes insipidus has occurred since 1913, when von der Velden1 in Germany and Farini and Ceccaroni2 in Italy, working independently, discovered the prompt, almost specific though temporary, control of excessive thirst and polyuria in patients suffering from diabetes insipidus following subcutaneous injections of extracts from the posterior lobe of the pituitary gland. Although the rôle of the posterior lobe in regulating normal water metabolism is still obscure, its antidiuretic effect with the adjustment of water balance and the correction of dehydration in diabetes insipidus has been abundantly confirmed.3 In seeking to remove the necessity for daily, painful hypodermic injections, attempts have been made to obtain the specific effect of the posterior lobe by the enteral administration of extracts4 and of fresh glands.5 All have proved totally ineffective or so variable in their action as to be impracticable.

Journal

JAMA – American Medical Association

Published: Mar 3, 1934

There are no references for this article.