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Desquamative Interstitial Pneumonia: Pathological Findings and Follow-Up in 13 Patients

Desquamative Interstitial Pneumonia: Pathological Findings and Follow-Up in 13 Patients Abstract Of 13 patients having desquamative interstitial pneumonia, six patients had abnormal serum antibody levels for extrapulmonary symptoms, while eight patients had interstitial fibrosis as a histological feature. Follow-up has shown that three patients died of disease and one shows progressive pulmonary insufficiency. The presence of pulmonary fibrosis in the biopsy specimen correlated with the clinical outcome. References 1. Liebow AA, et al: Desquamative interstitial pneumonia. Am J Med 39:369-404, 1965.Crossref 2. Farr GH, et al: Desquamative interstitial pneumonia: An electron-microscopic study. Am J Pathol 60:347-354, 1970. 3. Gaensler EA, et al: Desquamative interstitial pneumonia. N Engl J Med 274:113-128, 1966.Crossref 4. Klocke RA, et al: Desquamative interstitial pneumonia: A disease with a wide clinical spectrum. Ann Intern Med 66:498-506, 1967.Crossref 5. Scadding JC, Hinson KFW: Diffuse fibrosing alveolitis (diffuse interstitial fibrosis of the lungs): Correlation of histology at biopsy with prognosis. Thorax 22:291-304, 1967.Crossref 6. Patchefsky AS, et al: Desquamative interstitial pneumonia: Significance of intranuclear viral-like inclusion bodies. Ann Intern Med 74:322-327, 1971.Crossref 7. McNary WF Jr, Gaensler EA: Intranuclear inclusion bodies in desquamative interstitial pneumonia: Electron-microscopic observations. Ann Intern Med 74:404-407, 1971.Crossref 8. Kuisk H, Sanchez JS: Desquamative interstitial pneumonia and idiopathic diffuse pulmonary fibrosis. Am J Roentgenol Radium Ther Nucl Med 107:258-279, 1969.Crossref 9. Brown CH, Turner-Warwick M: The treatment of cryptogenic fibrosing alveolitis with immunosuppressant drugs. Q J Med 40:289-302, 1971. 10. Turner-Warwick M: Fibrosing alveolitis and chronic liver disease. Q J Med 37:133-149, 1968. 11. Gottlieb AJ, et al: Serologic factors in idiopathic diffuse interstitial pulmonary fibrosis. Am J Med 39:405-410, 1965.Crossref 12. Nagaya H, Sieker HO: Pathogenetic mechanisms of interstitial pulmonary fibrosis in patients with serum antinuclear factor: A histologic and clinical correlation. Am J Med 52:51-62, 1972.Crossref 13. Turner-Warwick M, Doniach D: Auto-antibody studies in interstitial pulmonary fibrosis. Br Med J 1:886-891, 1965.Crossref 14. Brewer DB, et al: Electron-microscopy of desquamative interstitial pneumonia. J Pathol 97:317-323, 1969.Crossref 15. Gould VE, et al: Desquamative interstitial pneumonia. Chest 59:349-352, 1971.Crossref 16. Huddy RB, Ahmed A: Fibrosing alveolitis and active chronic hepatitis without hyperglobulinemia. Postgrad Med J 47:363-364, 1971.Crossref 17. Tushan FS, et al: Serum IgA deficiency in a man with desquamative interstitial pneumonia. Am Rev Resp Dis 103:264-268, 1971. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Desquamative Interstitial Pneumonia: Pathological Findings and Follow-Up in 13 Patients

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Publisher
American Medical Association
Copyright
Copyright © 1973 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1973.03650080066013
Publisher site
See Article on Publisher Site

Abstract

Abstract Of 13 patients having desquamative interstitial pneumonia, six patients had abnormal serum antibody levels for extrapulmonary symptoms, while eight patients had interstitial fibrosis as a histological feature. Follow-up has shown that three patients died of disease and one shows progressive pulmonary insufficiency. The presence of pulmonary fibrosis in the biopsy specimen correlated with the clinical outcome. References 1. Liebow AA, et al: Desquamative interstitial pneumonia. Am J Med 39:369-404, 1965.Crossref 2. Farr GH, et al: Desquamative interstitial pneumonia: An electron-microscopic study. Am J Pathol 60:347-354, 1970. 3. Gaensler EA, et al: Desquamative interstitial pneumonia. N Engl J Med 274:113-128, 1966.Crossref 4. Klocke RA, et al: Desquamative interstitial pneumonia: A disease with a wide clinical spectrum. Ann Intern Med 66:498-506, 1967.Crossref 5. Scadding JC, Hinson KFW: Diffuse fibrosing alveolitis (diffuse interstitial fibrosis of the lungs): Correlation of histology at biopsy with prognosis. Thorax 22:291-304, 1967.Crossref 6. Patchefsky AS, et al: Desquamative interstitial pneumonia: Significance of intranuclear viral-like inclusion bodies. Ann Intern Med 74:322-327, 1971.Crossref 7. McNary WF Jr, Gaensler EA: Intranuclear inclusion bodies in desquamative interstitial pneumonia: Electron-microscopic observations. Ann Intern Med 74:404-407, 1971.Crossref 8. Kuisk H, Sanchez JS: Desquamative interstitial pneumonia and idiopathic diffuse pulmonary fibrosis. Am J Roentgenol Radium Ther Nucl Med 107:258-279, 1969.Crossref 9. Brown CH, Turner-Warwick M: The treatment of cryptogenic fibrosing alveolitis with immunosuppressant drugs. Q J Med 40:289-302, 1971. 10. Turner-Warwick M: Fibrosing alveolitis and chronic liver disease. Q J Med 37:133-149, 1968. 11. Gottlieb AJ, et al: Serologic factors in idiopathic diffuse interstitial pulmonary fibrosis. Am J Med 39:405-410, 1965.Crossref 12. Nagaya H, Sieker HO: Pathogenetic mechanisms of interstitial pulmonary fibrosis in patients with serum antinuclear factor: A histologic and clinical correlation. Am J Med 52:51-62, 1972.Crossref 13. Turner-Warwick M, Doniach D: Auto-antibody studies in interstitial pulmonary fibrosis. Br Med J 1:886-891, 1965.Crossref 14. Brewer DB, et al: Electron-microscopy of desquamative interstitial pneumonia. J Pathol 97:317-323, 1969.Crossref 15. Gould VE, et al: Desquamative interstitial pneumonia. Chest 59:349-352, 1971.Crossref 16. Huddy RB, Ahmed A: Fibrosing alveolitis and active chronic hepatitis without hyperglobulinemia. Postgrad Med J 47:363-364, 1971.Crossref 17. Tushan FS, et al: Serum IgA deficiency in a man with desquamative interstitial pneumonia. Am Rev Resp Dis 103:264-268, 1971.

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Aug 1, 1973

References