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Dermatoses in Patients Receiving Chemotherapy for Systemic Tuberculosis

Dermatoses in Patients Receiving Chemotherapy for Systemic Tuberculosis Abstract Of the two most important drugs used in the systemic therapy of tuberculosis, streptomycin has been reported to have caused dermatoses more frequently than nervous disorders, while administration of isonicotinic acid hydrazide (isoniazid) has been prone to result in more nervous disorders than dermatoses. Three types of cutaneous reaction to streptomycin were reported by Combes and associates1: (a) early polymorphous biotropic type of exanthem appearing before the 10th day, which responds to antihistaminics and does not require cessation of therapy; (b) exfoliative dermatitis after many weeks of treatment, necessitating its cessation, and (c) troublesome contact dermatitis of high incidence, especially in nurses continually in contact with the drug over long periods, necessitating either wearing of rubber gloves, frequent rotation of nurses, or removal from further contact. In the following year, Craps2 listed the dermatoses resulting from streptomycin therapy: simple pruritus; erythema, more References 1. Combes, F. C.; Canizares, O.; Shatin, H., and Kaufman, C.: Streptomycin in Dermatology: Its Value and Limitations , New York J. Med. , 48:2024-2028 ( (Sept. 15) ) 1948. 2. Craps, M.: La sensibilité de contact à la streptomycine , Arch. belges dermat. et syph. 5:262-271 ( (Dec.) ) 1949. 3. Strauss, M. J., and Warring, F. C., Jr.: Contact Dermatitis from Streptomycin , J. Invest. Dermat. , 9:3 ( (July) ) 1947.Crossref 4. Strauss, M. J., and Warring, F. C., Jr.: Epidermal Sensitization to Streptomycin , J. Invest. Dermat. 9:99-106 ( (Aug.) ) 1947.Crossref 5. The Effect of Streptomycin on Pulmonary Tuberculosis in Man: Preliminary Report of a Cooperative Study of 223 Cases by the Army, Navy and Veterans Administration, VA Technical Bulletin 10-37, Streptomycin Committee, Veterans Administration Central Office, Washington, D. C. Sept. 24, 1947. 6. Canizares, O., and Shatin, H.: Dermatitis Venenata Due to Streptomycin , Arch. Dermat. & Syph. , 56:676-677 ( (Nov.) ) 1947. 7. Berke, M., and Obermayer, M. E.: Contact-Type Sensitization to Antibiotic Agents , J. Invest. Dermat. 11:253-258, ( (Oct.) ) 1948. 8. Mitchell, H. S.: Streptomycin Dermatitis , J. Allergy , 22:71-73 ( (Jan.) ) 1951. 9. Heilman, D. H.; Heilman, F. R.; Hinshaw, H. C.; Nichols, D. R., and Herrell, W. E.: Streptomycin; Absorption, Diffusion, Excretion and Toxicity , Am. J. M. Sc. 210:576-584 ( (Nov.) ) 1945. 10. Watanuki, T., and Furuta, T.: A Case of Streptomycin Toxicosis Which Showed Symptoms Like Pemphigus , Tokoku M. J. 47:686-8, 1953. 11. Noguchi, Y., and Matsui, S.: Severe Pemphigoid Streptomycin Eruption Successfully Treated by IV ACTH (Corticotropin) , Yokohama M. Bull. 4:234-237, 1953. 12. Morris, G. E.: Pellagrous Dermatitis Following Use of Antibiotics , GP 9:71-73 ( (May) ) 1954. 13. Jordan, J. W.: Cutaneous Allergy from Local Contact with Isonicotinic Acid Hydrazid , J. A. M. A. 149:1316 ( (Aug. 2) ) 1952. 14. Münch, H.: Isonicotinsäurehydrazid Kontaktdermatitis , Internat. Arch. Allergy 5:298-304, 1954. 15. Becker, S. W., and Obermayer, M. E.: Modern Dermatology and Syphilology , Ed. 2, Philadelphia, J. B. Lippincott Company, 1947. 16. Ganguli, L. K.: Streptomycin Encephalopathy , J. Indian M. A. 24:307-309, 1955. 17. Poursines, Y.; Crémieux, A.; Alliez, J., and Roger, J.: Accès confusionnels récidivants au cours du traitement d'une tuberculose rénal , Ann. méd. psychol. , 112:707-711, 1954. 18. Hinshaw, H. C., and Feldman, W. H.: Streptomycin in Treatment of Clinical Tuberculosis. A Preliminary Report , Proc. Staff Meet. Mayo Clin. 20:313-318 ( (Sept. 5) ) 1945. 19. Zabad, M.: Psychosis with Isoniazid Therapy, Correspondence , Lancet , 1:295 ( (Feb. 7) ) 1953. 20. Wiedorn, W. S., and Ervin, F.: Schizophrenic-like Psychotic Reactions with Administration of Isoniazid , A. M. A. Arch. Neurol. & Psychiat. 72:321-324 ( (Sept.) ) 1954. 21. Hunter, R. H.: Confusional Psychosis with Residual Organic Cerebral Impairment Following Isoniazid Therapy , Lancet 2:960-962 ( (Nov. 15) ) 1952. 22. Hayes, J. W.: Isoniazid Delirium, Correspondence , Am. Rev. Tuberc. 69:845-846 ( (May) ) 1954. 23. Vysniauskas, C., and Brueckner, H. H.: Severe Reactions of the Central Nervous System Following Isoniazid Treatment , Am. Rev. Tuberc. 69:759-765 ( (May) ) 1954. 24. Sutton, P. H., and Beattie, P. H.: Optic Atrophy After Administration of Isoniazid with PAS , Lancet , 1:650-651 ( (March 26) ) 1955.Crossref 25. Fisher, M. M.; Mammlok, E. R.; Tendlau, A.; Terbrok, H. E.; Drumm, A. E., and Spiegelman, A.: Isoniazid and Its Derivatives in Tuberculosis: An Evaluation of the Side-Effects in Relation to Peripheral Circulation , New York J. Med. 52:1519-1527 ( (June 15) ) 1952. 26. Lubing, H. N.: Peripheral Neuropathy in Tuberculosis Patients Treated with Isoniazid , Am. Rev. Tuberc. 68:458-461 ( (Sept.) ) 1953. 27. Biehl, J. P., and Vilter, R. W.: Effect of Isoniazid on Vitamin B6 Metabolism: Its Possible Significance in Producing Isoniazid Neuritis , Proc. Soc. Exper. Biol. & Med. 85:389-392 ( (March) ) 1954. 28. Simon, R.: An Investigation of Some Psychological Effects Accompanying Isoniazid Therapy on Tuberculous Patients , Am. J. M. Sc. 227:493-502 ( (May) ) 1954. 29. Zitrin, A., and Thompson, D. S.: Effects of Isonicotinic Acid Hydrazides on Mental Status of Tuberculous Patients , J. A. M. A. 161:204-10 ( (May 19) ) 1956. 30. Pleasure, H.: Psychiatric and Neurological Side-effects of Isoniazid and Iproniazid , A. M. A. Arch. Neurol. & Psychiat. 72:313-320 ( (Sept.) ) 1954. 31. Biehl, J. P., and Skavlem, J. H.: Toxicity of Isoniazid, Correspondence , Am. Rev. Tuberc. 68:296-297 ( (Aug.) ) 1953. 32. Hook, O.: Polyneuritis Caused by Hydrazide of Isonicotinic Acid , Acta med. scandinav. 147:167-74, 1953. 33. Cohen, R. C.: Desensitization of Hospital Staff to Streptomycin , Tubercle 35:142-145 ( (June) ) 1954. 34. Simon, S. W.: Skin Sensitivity to Streptomycin , J. Allergy 20:56-61 ( (Jan.) ) 1949. 35. Wilkinson, M. C.: Sensitivity to Streptomycin , Brit. M. J. , 2:707 ( (Sept. 24) ) 1949. 36. Russell, B.: Desensitization to Streptomycin and PAS , Brit. M. J. 2:1322 ( (Dec. 12) ) 1953. 37. Rosen, F. L.: Sensitivity to Streptomycin: Anaphylactic Shock Following Intracutaneous Test , J. A. M. A. 137:1128 ( (July 24) ) 1948. 38. Rauchwerger, S. M.; Erskine, F. A., and Nails, W. L.: Streptomycin Sensitivity , J. A. M. A. , 136:614-615 ( (Feb. 28) ) 1948. 39. Crofton, J. W.: Desensitization to Streptomycin and PAS , Brit. M. J. 2:1014-1017 ( (Nov. 7) ) 1953. 40. Röckl, H., and Sixt, I.: Kontaktekzem-Allergie gegenueber Isonikotinsäure Hydrazid: Kasuisticher Bericht , Dermat. Wchnschr. 129:296-297, 1954. 41. O'Doherty, B.: Simultaneous Streptomycin-PAS Sensitivity , J. Irish M. A. 35:385 ( (Dec.) ) 1954. 42. Keller, P.: Erythrodermie nach Neoteben , Dermat. Wchnschr. 131:193-195, 1955. 43. Brenn, H., and Röckl, H.: Urticaria durch Isonikotinsäurehydrazid (Neoteben) mit gelungener passiver Übertragung , Hautarzt 4:390-391 ( (Aug.) ) 1953. 44. Keeffer, C. S.; Blake, F. G.; Lockwood, J. S.; Long, P. H.; Marshall, E. K., Jr., and Wood, W. B., Jr.: Streptomycin in the Treatment of Infections , J. A. M. A. 132:4-11 ( (Sept. 7) )Crossref 45. 70-77 (Sept. 14) 1946 46. Howlett, K. S., and O'Connor, J. B.: The Treatment of Tuberculosis, in Streptomycin and Dihydrostreptomycin in Tuberculosis , edited by H. M. Riggins and H. C. Hinshaw, New York, National Tuberculosis Association, 1949. 47. Mullin, E. W.; Wright, K. W., and Bunn, P. A.: The Long-Term Toxicity and Metabolic Effects of Isoniazid in Adults , Am. Rev. Tuber. 67:652-656 ( (May) ) 1953. 48. Jeffery, B.; Borrie, P., and MacDonald, N.: Acquired Sensitivity to Sodium PAS, Streptomycin, and Penicillin , Brit. M. J. 2:647-649 ( (Sept. 20) ) 1952.Crossref 49. Julian, D. G.: Acquired Sensitivity to Streptomycin and Sodium PAS , Brit. M. J. 2:476-477 ( (Aug. 30) ) 1952.Crossref 50. Livingston, R., and Street, E. W.: Acquired Idiosyncrasy to Sodium p-Aminosalicylate , Lancet 2:308-309 ( (Aug. 19) ) 1950. 51. Bauer, W.: Über einen Fall von PASAllergie mit universeller Dermatitis (Nachtrag) , Med. Monatsschr. 7:382 ( (June) ) 1953. 52. Koenig, R. P.: Allergic Reaction to Para-Aminosalicylic Acid; Report of Case , Minnesota Med. 36:850 ( (Aug.) ) 1953. 53. Kierland, R. R., and Carr, D. T.: Reactions to Para-Amino Salicylic Acid , Proc. Staff Meet. Mayo Clin. 24:539 ( (Oct. 12) ) 1949 54. Warring, F. C., and Howlett, K. S., Jr.: Allergic Reactions to Para-Aminosalicylic Acid , Am. Rev. Tuberc. 65:235-249 ( (March) ) 1952. 55. Shatin, H.; Canizares, O., and Worthington, E. L.: Lichen-Planus-like Drug Eruption Due to Para-Amino Salicylic Acid: Report of 5 Cases, 2 Showing Mouth Lesions , J. Invest. Dermat. 21:135-138 ( (Sept.) ) 1953.Crossref 56. Bulley, K. G.: Near-Fatal Shock from PAS, Followed by Guillain-Barré's Syndrome , Am. Rev. Tuberc. 69:455-457 ( (March) ) 1954. 57. Cuthbert, J.: Acquired Idiosyncrasy to Sodium p-Aminosalicylate , Lancet 2:209-211 ( (Aug. 5) ) 1950.Crossref 58. Horne, N. W.: Complications of Para-Aminosalicylic Acid Therapy , Lancet 2:348-349 ( (Aug. 20) ) 1949. 59. Korst, D. R.: Severe Reactions to Para-Aminosalicylic Acid: A Case Report and Brief Review of Literature , Ann. Int. Med. , 40:1011-1016 ( (May) ) 1954.Crossref 60. Kniest, W.: Schwere allergische Reaktionen gegen p-Aminosalizysäure , Deutsche med. Wchnschr. 77:676-677 ( (May 23) ) 1952.Crossref 61. Goldman, L.: Some Autonomic Nervous System Reactions in Selected Cases of Cheiropompholyx , Med. Bull. Univ. Cincinnati 8:79-88 ( (Feb.) ) 1941. 62. French, J. D.; Porter, R. W.; Cavanaugh, E. B., and Longmire, R. L.: Experimental Observations on "Psychosomatic" Mechanisms: I. Gastrointestinal Disturbances , A. M. A. Arch. Neurol. & Psychiat. 72:267-281 ( (Sept.) ) 1954. 63. Obermayer, M. E.: Psychocutaneous Medicine , Springfield, Ill., Charles C Thomas, Publisher, 1955. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology American Medical Association

Dermatoses in Patients Receiving Chemotherapy for Systemic Tuberculosis

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American Medical Association
Copyright
Copyright © 1957 American Medical Association. All Rights Reserved.
ISSN
0096-5359
DOI
10.1001/archderm.1957.01550150017002
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Abstract

Abstract Of the two most important drugs used in the systemic therapy of tuberculosis, streptomycin has been reported to have caused dermatoses more frequently than nervous disorders, while administration of isonicotinic acid hydrazide (isoniazid) has been prone to result in more nervous disorders than dermatoses. Three types of cutaneous reaction to streptomycin were reported by Combes and associates1: (a) early polymorphous biotropic type of exanthem appearing before the 10th day, which responds to antihistaminics and does not require cessation of therapy; (b) exfoliative dermatitis after many weeks of treatment, necessitating its cessation, and (c) troublesome contact dermatitis of high incidence, especially in nurses continually in contact with the drug over long periods, necessitating either wearing of rubber gloves, frequent rotation of nurses, or removal from further contact. In the following year, Craps2 listed the dermatoses resulting from streptomycin therapy: simple pruritus; erythema, more References 1. Combes, F. C.; Canizares, O.; Shatin, H., and Kaufman, C.: Streptomycin in Dermatology: Its Value and Limitations , New York J. Med. , 48:2024-2028 ( (Sept. 15) ) 1948. 2. Craps, M.: La sensibilité de contact à la streptomycine , Arch. belges dermat. et syph. 5:262-271 ( (Dec.) ) 1949. 3. Strauss, M. J., and Warring, F. C., Jr.: Contact Dermatitis from Streptomycin , J. Invest. Dermat. , 9:3 ( (July) ) 1947.Crossref 4. Strauss, M. J., and Warring, F. C., Jr.: Epidermal Sensitization to Streptomycin , J. Invest. Dermat. 9:99-106 ( (Aug.) ) 1947.Crossref 5. The Effect of Streptomycin on Pulmonary Tuberculosis in Man: Preliminary Report of a Cooperative Study of 223 Cases by the Army, Navy and Veterans Administration, VA Technical Bulletin 10-37, Streptomycin Committee, Veterans Administration Central Office, Washington, D. C. Sept. 24, 1947. 6. Canizares, O., and Shatin, H.: Dermatitis Venenata Due to Streptomycin , Arch. Dermat. & Syph. , 56:676-677 ( (Nov.) ) 1947. 7. Berke, M., and Obermayer, M. E.: Contact-Type Sensitization to Antibiotic Agents , J. Invest. Dermat. 11:253-258, ( (Oct.) ) 1948. 8. Mitchell, H. S.: Streptomycin Dermatitis , J. Allergy , 22:71-73 ( (Jan.) ) 1951. 9. Heilman, D. H.; Heilman, F. R.; Hinshaw, H. C.; Nichols, D. R., and Herrell, W. E.: Streptomycin; Absorption, Diffusion, Excretion and Toxicity , Am. J. M. Sc. 210:576-584 ( (Nov.) ) 1945. 10. Watanuki, T., and Furuta, T.: A Case of Streptomycin Toxicosis Which Showed Symptoms Like Pemphigus , Tokoku M. J. 47:686-8, 1953. 11. Noguchi, Y., and Matsui, S.: Severe Pemphigoid Streptomycin Eruption Successfully Treated by IV ACTH (Corticotropin) , Yokohama M. Bull. 4:234-237, 1953. 12. Morris, G. E.: Pellagrous Dermatitis Following Use of Antibiotics , GP 9:71-73 ( (May) ) 1954. 13. Jordan, J. W.: Cutaneous Allergy from Local Contact with Isonicotinic Acid Hydrazid , J. A. M. A. 149:1316 ( (Aug. 2) ) 1952. 14. Münch, H.: Isonicotinsäurehydrazid Kontaktdermatitis , Internat. Arch. Allergy 5:298-304, 1954. 15. Becker, S. W., and Obermayer, M. E.: Modern Dermatology and Syphilology , Ed. 2, Philadelphia, J. B. Lippincott Company, 1947. 16. Ganguli, L. K.: Streptomycin Encephalopathy , J. Indian M. A. 24:307-309, 1955. 17. Poursines, Y.; Crémieux, A.; Alliez, J., and Roger, J.: Accès confusionnels récidivants au cours du traitement d'une tuberculose rénal , Ann. méd. psychol. , 112:707-711, 1954. 18. Hinshaw, H. C., and Feldman, W. H.: Streptomycin in Treatment of Clinical Tuberculosis. A Preliminary Report , Proc. Staff Meet. Mayo Clin. 20:313-318 ( (Sept. 5) ) 1945. 19. Zabad, M.: Psychosis with Isoniazid Therapy, Correspondence , Lancet , 1:295 ( (Feb. 7) ) 1953. 20. Wiedorn, W. S., and Ervin, F.: Schizophrenic-like Psychotic Reactions with Administration of Isoniazid , A. M. A. Arch. Neurol. & Psychiat. 72:321-324 ( (Sept.) ) 1954. 21. Hunter, R. H.: Confusional Psychosis with Residual Organic Cerebral Impairment Following Isoniazid Therapy , Lancet 2:960-962 ( (Nov. 15) ) 1952. 22. Hayes, J. W.: Isoniazid Delirium, Correspondence , Am. Rev. Tuberc. 69:845-846 ( (May) ) 1954. 23. Vysniauskas, C., and Brueckner, H. H.: Severe Reactions of the Central Nervous System Following Isoniazid Treatment , Am. Rev. Tuberc. 69:759-765 ( (May) ) 1954. 24. Sutton, P. H., and Beattie, P. H.: Optic Atrophy After Administration of Isoniazid with PAS , Lancet , 1:650-651 ( (March 26) ) 1955.Crossref 25. Fisher, M. M.; Mammlok, E. R.; Tendlau, A.; Terbrok, H. E.; Drumm, A. E., and Spiegelman, A.: Isoniazid and Its Derivatives in Tuberculosis: An Evaluation of the Side-Effects in Relation to Peripheral Circulation , New York J. Med. 52:1519-1527 ( (June 15) ) 1952. 26. Lubing, H. N.: Peripheral Neuropathy in Tuberculosis Patients Treated with Isoniazid , Am. Rev. Tuberc. 68:458-461 ( (Sept.) ) 1953. 27. Biehl, J. P., and Vilter, R. W.: Effect of Isoniazid on Vitamin B6 Metabolism: Its Possible Significance in Producing Isoniazid Neuritis , Proc. Soc. Exper. Biol. & Med. 85:389-392 ( (March) ) 1954. 28. Simon, R.: An Investigation of Some Psychological Effects Accompanying Isoniazid Therapy on Tuberculous Patients , Am. J. M. Sc. 227:493-502 ( (May) ) 1954. 29. Zitrin, A., and Thompson, D. S.: Effects of Isonicotinic Acid Hydrazides on Mental Status of Tuberculous Patients , J. A. M. A. 161:204-10 ( (May 19) ) 1956. 30. Pleasure, H.: Psychiatric and Neurological Side-effects of Isoniazid and Iproniazid , A. M. A. Arch. Neurol. & Psychiat. 72:313-320 ( (Sept.) ) 1954. 31. Biehl, J. P., and Skavlem, J. H.: Toxicity of Isoniazid, Correspondence , Am. Rev. Tuberc. 68:296-297 ( (Aug.) ) 1953. 32. Hook, O.: Polyneuritis Caused by Hydrazide of Isonicotinic Acid , Acta med. scandinav. 147:167-74, 1953. 33. Cohen, R. C.: Desensitization of Hospital Staff to Streptomycin , Tubercle 35:142-145 ( (June) ) 1954. 34. Simon, S. W.: Skin Sensitivity to Streptomycin , J. Allergy 20:56-61 ( (Jan.) ) 1949. 35. Wilkinson, M. C.: Sensitivity to Streptomycin , Brit. M. J. , 2:707 ( (Sept. 24) ) 1949. 36. Russell, B.: Desensitization to Streptomycin and PAS , Brit. M. J. 2:1322 ( (Dec. 12) ) 1953. 37. Rosen, F. L.: Sensitivity to Streptomycin: Anaphylactic Shock Following Intracutaneous Test , J. A. M. A. 137:1128 ( (July 24) ) 1948. 38. Rauchwerger, S. M.; Erskine, F. A., and Nails, W. L.: Streptomycin Sensitivity , J. A. M. A. , 136:614-615 ( (Feb. 28) ) 1948. 39. Crofton, J. W.: Desensitization to Streptomycin and PAS , Brit. M. J. 2:1014-1017 ( (Nov. 7) ) 1953. 40. Röckl, H., and Sixt, I.: Kontaktekzem-Allergie gegenueber Isonikotinsäure Hydrazid: Kasuisticher Bericht , Dermat. Wchnschr. 129:296-297, 1954. 41. O'Doherty, B.: Simultaneous Streptomycin-PAS Sensitivity , J. Irish M. A. 35:385 ( (Dec.) ) 1954. 42. Keller, P.: Erythrodermie nach Neoteben , Dermat. Wchnschr. 131:193-195, 1955. 43. Brenn, H., and Röckl, H.: Urticaria durch Isonikotinsäurehydrazid (Neoteben) mit gelungener passiver Übertragung , Hautarzt 4:390-391 ( (Aug.) ) 1953. 44. Keeffer, C. S.; Blake, F. G.; Lockwood, J. S.; Long, P. H.; Marshall, E. K., Jr., and Wood, W. B., Jr.: Streptomycin in the Treatment of Infections , J. A. M. A. 132:4-11 ( (Sept. 7) )Crossref 45. 70-77 (Sept. 14) 1946 46. Howlett, K. S., and O'Connor, J. B.: The Treatment of Tuberculosis, in Streptomycin and Dihydrostreptomycin in Tuberculosis , edited by H. M. Riggins and H. C. Hinshaw, New York, National Tuberculosis Association, 1949. 47. Mullin, E. W.; Wright, K. W., and Bunn, P. A.: The Long-Term Toxicity and Metabolic Effects of Isoniazid in Adults , Am. Rev. Tuber. 67:652-656 ( (May) ) 1953. 48. Jeffery, B.; Borrie, P., and MacDonald, N.: Acquired Sensitivity to Sodium PAS, Streptomycin, and Penicillin , Brit. M. J. 2:647-649 ( (Sept. 20) ) 1952.Crossref 49. Julian, D. G.: Acquired Sensitivity to Streptomycin and Sodium PAS , Brit. M. J. 2:476-477 ( (Aug. 30) ) 1952.Crossref 50. Livingston, R., and Street, E. W.: Acquired Idiosyncrasy to Sodium p-Aminosalicylate , Lancet 2:308-309 ( (Aug. 19) ) 1950. 51. Bauer, W.: Über einen Fall von PASAllergie mit universeller Dermatitis (Nachtrag) , Med. Monatsschr. 7:382 ( (June) ) 1953. 52. Koenig, R. P.: Allergic Reaction to Para-Aminosalicylic Acid; Report of Case , Minnesota Med. 36:850 ( (Aug.) ) 1953. 53. Kierland, R. R., and Carr, D. T.: Reactions to Para-Amino Salicylic Acid , Proc. Staff Meet. Mayo Clin. 24:539 ( (Oct. 12) ) 1949 54. Warring, F. C., and Howlett, K. S., Jr.: Allergic Reactions to Para-Aminosalicylic Acid , Am. Rev. Tuberc. 65:235-249 ( (March) ) 1952. 55. Shatin, H.; Canizares, O., and Worthington, E. L.: Lichen-Planus-like Drug Eruption Due to Para-Amino Salicylic Acid: Report of 5 Cases, 2 Showing Mouth Lesions , J. Invest. Dermat. 21:135-138 ( (Sept.) ) 1953.Crossref 56. Bulley, K. G.: Near-Fatal Shock from PAS, Followed by Guillain-Barré's Syndrome , Am. Rev. Tuberc. 69:455-457 ( (March) ) 1954. 57. Cuthbert, J.: Acquired Idiosyncrasy to Sodium p-Aminosalicylate , Lancet 2:209-211 ( (Aug. 5) ) 1950.Crossref 58. Horne, N. W.: Complications of Para-Aminosalicylic Acid Therapy , Lancet 2:348-349 ( (Aug. 20) ) 1949. 59. Korst, D. R.: Severe Reactions to Para-Aminosalicylic Acid: A Case Report and Brief Review of Literature , Ann. Int. Med. , 40:1011-1016 ( (May) ) 1954.Crossref 60. Kniest, W.: Schwere allergische Reaktionen gegen p-Aminosalizysäure , Deutsche med. Wchnschr. 77:676-677 ( (May 23) ) 1952.Crossref 61. Goldman, L.: Some Autonomic Nervous System Reactions in Selected Cases of Cheiropompholyx , Med. Bull. Univ. Cincinnati 8:79-88 ( (Feb.) ) 1941. 62. French, J. D.; Porter, R. W.; Cavanaugh, E. B., and Longmire, R. L.: Experimental Observations on "Psychosomatic" Mechanisms: I. Gastrointestinal Disturbances , A. M. A. Arch. Neurol. & Psychiat. 72:267-281 ( (Sept.) ) 1954. 63. Obermayer, M. E.: Psychocutaneous Medicine , Springfield, Ill., Charles C Thomas, Publisher, 1955.

Journal

A.M.A. Archives of DermatologyAmerican Medical Association

Published: Mar 1, 1957

References