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Dermal and Epidermal Types of Erythema Multiforme

Dermal and Epidermal Types of Erythema Multiforme This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.— In their paper in the Archives titled "Dermal and Epidermal Types of Erythema Multiforme" (109:682-688, 1974), Orfanos et al attempt to reconcile contradictory reports of histological changes in erythema multiforme by positing two different histologic types of erythema multiforme. In one type, the blister is said to occur in the papillary dermis as a result of dermal edema caused by increased vascular permeability. In describing the second type, Orfanis et al write that "Ackerman and his coworkers have recently reported that liquefaction degeneration at the dermoepidermal interface was the most characteristic light microscopical feature in early target lesions and that vascular changes were lacking." This is not a completely accurate restatement of our findings, published in the British Journal of Dermatology (84:554-566, 1971). We wrote:In summary, the eruption of erythema multiforme exudativum may vary from erythematous edematous papules, with or without "iris" and "target" lesions, to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Dermal and Epidermal Types of Erythema Multiforme

Archives of Dermatology , Volume 111 (6) – Jun 1, 1975

Dermal and Epidermal Types of Erythema Multiforme

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.— In their paper in the Archives titled "Dermal and Epidermal Types of Erythema Multiforme" (109:682-688, 1974), Orfanos et al attempt to reconcile contradictory reports of histological changes in erythema multiforme by positing two different histologic types of erythema multiforme. In one type, the blister is said to...
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Publisher
American Medical Association
Copyright
Copyright © 1975 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1975.01630180123026
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.— In their paper in the Archives titled "Dermal and Epidermal Types of Erythema Multiforme" (109:682-688, 1974), Orfanos et al attempt to reconcile contradictory reports of histological changes in erythema multiforme by positing two different histologic types of erythema multiforme. In one type, the blister is said to occur in the papillary dermis as a result of dermal edema caused by increased vascular permeability. In describing the second type, Orfanis et al write that "Ackerman and his coworkers have recently reported that liquefaction degeneration at the dermoepidermal interface was the most characteristic light microscopical feature in early target lesions and that vascular changes were lacking." This is not a completely accurate restatement of our findings, published in the British Journal of Dermatology (84:554-566, 1971). We wrote:In summary, the eruption of erythema multiforme exudativum may vary from erythematous edematous papules, with or without "iris" and "target" lesions, to

Journal

Archives of DermatologyAmerican Medical Association

Published: Jun 1, 1975

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