Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Deposition of Aerosols in Pulmonary Disease

Deposition of Aerosols in Pulmonary Disease Abstract Pathological conditions may possibly affect the deposition of aerosols in the human respiratory tract. Respiratory disease may cause alterations in the pattern of breathing and changes in airway diameter and geometry. These alterations may influence the main mechanisms of deposition—inertial impaction, gravitational sedimentation, Brownian diffusion, and turbulent diffusion. References 1. Lourenco RB, Klimek MF, Borowski CJ: Deposition and clearance of two micron particles in the tracheo-bronchial tree of normal subjects, smokers and nonsmokers. J Clin Invest 50:1411-1420, 1972.Crossref 2. Hatch TF, Gross P: Pulmonary Deposition and Retention of Inhaled Aerosols . New York, Academic Press Inc, 1964, pp 31-43. 3. Owen PR: Turbulent flow and particle deposition in the trachea , in Wolstenholme GEW, Knight J (eds): Circulatory and Respiratory Mass Transport . Boston, Little Brown & Co, 1969, pp 236-252. 4. Lippmann M, Albert RE: The effect of particle size on the regional deposition of inhaled aerosols in the human respiratory tract. Am Ind Hyg Assoc J 30:257-275, 1969.Crossref 5. Lourenço RV: Distribution and clearance of aerosols. Am Rev Resp Dis 101:460-461, 1969. 6. Landau LD, Lifshitz EM: Fluid mechanics , in Course in Theoretical Physics . London, Pergamon Press, 1959, vol 6, pp 102-144. 7. Binder RC: Fluid Mechanics , ed 4. Englewood Cliffs, NJ, Prentice Hall, 1962, p 107. 8. Dekker E: Transition between laminar and turbulent flow in human trachea. J Appl Physiol 16:1060-1064, 1961. 9. Ingelstedt S, Toremalm NG: Air flow patterns and heat transfer within the respiratory tract: A new method for experimental studies in models. Acta Physiol Scand 51:204-217, 1961.Crossref 10. Sehmel GA: Complexities of particle deposition and re-entrainment in turbulent pipe flow. Aerosol Sci 2:63-72, 1971.Crossref 11. Beeckmans JM: The deposition of aerosols in the respiratory tract: I. Mathematical analysis and comparison with experimental data. Can J Physiol Pharmacol 43:157-172, 1965.Crossref 12. Silverman L, Billings CE: Pattern of airflow in the respiratory tract , in Davies CN (ed): Inhaled Particles and Vapours . Oxford, Pergamon Press, 1961, pp 9-45. 13. Dennis WL: The effect of breathing rate on the deposition of particles in the human respiratory system , in Walton WH (ed): Inhaled Particles III . Surrey, Greshman Press, 1970, vol 1, pp 91-102. 14. Wilson IB, LaMer VK: The retention of aerosol particles in the human respiratory tract as a function of particle radius. J Ind Hyg Tox 30:265-280, 1948. 15. Sudlow MF, Olson DE, Schroter RC: Fluid mechanics of bronchial air-flow , in Walton WH (ed): Inhaled Particles III . Surrey, Gresham Press, 1970, vol 1, pp 19-29. 16. Weibel ER: Morphometry of the Human Lung . New York, Academic Press Inc, 1963, pp 110-143. 17. Landahl HD: On the removal of air-borne droplets by the human respiratory tract: I. The lung. Bull Math Biophys 12:43-56, 1950.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Deposition of Aerosols in Pulmonary Disease

Loading next page...
 
/lp/american-medical-association/deposition-of-aerosols-in-pulmonary-disease-SRTCHr1pBV
Publisher
American Medical Association
Copyright
Copyright © 1973 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1973.00320070084009
Publisher site
See Article on Publisher Site

Abstract

Abstract Pathological conditions may possibly affect the deposition of aerosols in the human respiratory tract. Respiratory disease may cause alterations in the pattern of breathing and changes in airway diameter and geometry. These alterations may influence the main mechanisms of deposition—inertial impaction, gravitational sedimentation, Brownian diffusion, and turbulent diffusion. References 1. Lourenco RB, Klimek MF, Borowski CJ: Deposition and clearance of two micron particles in the tracheo-bronchial tree of normal subjects, smokers and nonsmokers. J Clin Invest 50:1411-1420, 1972.Crossref 2. Hatch TF, Gross P: Pulmonary Deposition and Retention of Inhaled Aerosols . New York, Academic Press Inc, 1964, pp 31-43. 3. Owen PR: Turbulent flow and particle deposition in the trachea , in Wolstenholme GEW, Knight J (eds): Circulatory and Respiratory Mass Transport . Boston, Little Brown & Co, 1969, pp 236-252. 4. Lippmann M, Albert RE: The effect of particle size on the regional deposition of inhaled aerosols in the human respiratory tract. Am Ind Hyg Assoc J 30:257-275, 1969.Crossref 5. Lourenço RV: Distribution and clearance of aerosols. Am Rev Resp Dis 101:460-461, 1969. 6. Landau LD, Lifshitz EM: Fluid mechanics , in Course in Theoretical Physics . London, Pergamon Press, 1959, vol 6, pp 102-144. 7. Binder RC: Fluid Mechanics , ed 4. Englewood Cliffs, NJ, Prentice Hall, 1962, p 107. 8. Dekker E: Transition between laminar and turbulent flow in human trachea. J Appl Physiol 16:1060-1064, 1961. 9. Ingelstedt S, Toremalm NG: Air flow patterns and heat transfer within the respiratory tract: A new method for experimental studies in models. Acta Physiol Scand 51:204-217, 1961.Crossref 10. Sehmel GA: Complexities of particle deposition and re-entrainment in turbulent pipe flow. Aerosol Sci 2:63-72, 1971.Crossref 11. Beeckmans JM: The deposition of aerosols in the respiratory tract: I. Mathematical analysis and comparison with experimental data. Can J Physiol Pharmacol 43:157-172, 1965.Crossref 12. Silverman L, Billings CE: Pattern of airflow in the respiratory tract , in Davies CN (ed): Inhaled Particles and Vapours . Oxford, Pergamon Press, 1961, pp 9-45. 13. Dennis WL: The effect of breathing rate on the deposition of particles in the human respiratory system , in Walton WH (ed): Inhaled Particles III . Surrey, Greshman Press, 1970, vol 1, pp 91-102. 14. Wilson IB, LaMer VK: The retention of aerosol particles in the human respiratory tract as a function of particle radius. J Ind Hyg Tox 30:265-280, 1948. 15. Sudlow MF, Olson DE, Schroter RC: Fluid mechanics of bronchial air-flow , in Walton WH (ed): Inhaled Particles III . Surrey, Gresham Press, 1970, vol 1, pp 19-29. 16. Weibel ER: Morphometry of the Human Lung . New York, Academic Press Inc, 1963, pp 110-143. 17. Landahl HD: On the removal of air-borne droplets by the human respiratory tract: I. The lung. Bull Math Biophys 12:43-56, 1950.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Jan 1, 1973

References