Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Dementias Appear to Have Individual Profiles in Single Photon Emission Computed Tomography

Dementias Appear to Have Individual Profiles in Single Photon Emission Computed Tomography A NUMBER OF researchers are seeking clinical applications for single photon emission computed tomographic (SPECT) images of demented patients. They have found that dementias have somewhat individual SPECT profiles. The challenge now, they say, is to determine if the SPECT information is meaningful to the clinician and to develop more specific radiotracers, such as tracers for individual neuroreceptors. The initial work was done with positron emission tomography (PET), a sometimes more sensitive, but much more expensive technique. Recently, a number of centers began trying to duplicate the PET findings using SPECT. Developing SPECT could actually make dementia scanning fairly available, they say. Radiologists estimate that three fourths of the nation's nuclear medicine departments have SPECT scanning machines—either rotating or multiaperture gamma cameras. Radioligand Now Available The trick was to develop a radioligand for imaging blood perfusion that would pass through the blood-brain barrier—a lipophilic molecule—but that would stay in the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Dementias Appear to Have Individual Profiles in Single Photon Emission Computed Tomography

Kirn, Timothy F.
JAMA , Volume 261 (7) – Feb 17, 1989
Download PDF
2 pages

Loading next page...
 
/lp/american-medical-association/dementias-appear-to-have-individual-profiles-in-single-photon-emission-SEviJCnIb4

References (0)

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
American Medical Association
Copyright
Copyright © 1989 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1989.03420070015004
Publisher site
See Article on Publisher Site

Abstract

A NUMBER OF researchers are seeking clinical applications for single photon emission computed tomographic (SPECT) images of demented patients. They have found that dementias have somewhat individual SPECT profiles. The challenge now, they say, is to determine if the SPECT information is meaningful to the clinician and to develop more specific radiotracers, such as tracers for individual neuroreceptors. The initial work was done with positron emission tomography (PET), a sometimes more sensitive, but much more expensive technique. Recently, a number of centers began trying to duplicate the PET findings using SPECT. Developing SPECT could actually make dementia scanning fairly available, they say. Radiologists estimate that three fourths of the nation's nuclear medicine departments have SPECT scanning machines—either rotating or multiaperture gamma cameras. Radioligand Now Available The trick was to develop a radioligand for imaging blood perfusion that would pass through the blood-brain barrier—a lipophilic molecule—but that would stay in the

Journal

JAMA – American Medical Association

Published: Feb 17, 1989

There are no references for this article.