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Delay in the Diagnosis of Pediatric Brain Tumors

Delay in the Diagnosis of Pediatric Brain Tumors Abstract • The interval from the onset of symptoms to the diagnosis in 79 children with primary brain tumors was compared with that in 45 children with Wilms' tumor and 123 children with acute leukemia. The patients with brain tumors had a significant delay from symptom onset to diagnosis. Only 38% of primary brain tumors were diagnosed within the first month after the onset of symptoms. In contrast, 84% of Wilms' tumors and 80% of cases of acute leukemia were diagnosed within one month of the onset of symptoms. Early detection of brain tumors is important as it may have a significant bearing on clinical outcome. (AJDC 1986;140:684-686) References 1. Patitch HS, Berg BO: Brain stem tumors of childhood and adolescence . AJDC 1970;119: 465-472. 2. Levine AS: Cancer in the Young . New York, Masson Publishers USA Inc, 1982, pp 695-697. 3. Tomida T: Statistical analysis of symptoms and signs in cerebellar astrocytoma and medulloblastoma , in Amador LV (ed): Brain Tumors in the Young . Springfield, Ill, Charles C Thomas Publisher, 1983, pp 514-525. 4. Villani R, Gaini SN, Tomei G: Follow-up study of brain stem tumors in children . Childs Brain 1975;1:126-135. 5. Gjerris F: Clinical aspects and long-term prognosis of infratentorial intracranial tumors in infancy and childhood . Acta Neurol Scand 1978;57:31-52.Crossref 6. Walker R, Lieberman AN, Pintor GA, et al: Transient neurologic disturbances, brain tumors, and normal computed tomography scans . Cancer 1983;52:1502-1506.Crossref 7. Weinblatt ME, Ortega JA, Miller JH, et al: The reliability of noninvasive diagnostic procedures in children with brain tumors . Am J Pediatr Hematol Oncol 1982;4:367-372.Crossref 8. Bailey CC: Brain tumors in childhood . Rec Results Cancer Res 1983;88:64-68. 9. Kopelson G, Lingood RM, Kleinman GM: Medulloblastoma: Identification of prognostic subgroups and implications for multimodal management . Cancer 1983;51:312-319.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1986 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1986.02140210082031
Publisher site
See Article on Publisher Site

Abstract

Abstract • The interval from the onset of symptoms to the diagnosis in 79 children with primary brain tumors was compared with that in 45 children with Wilms' tumor and 123 children with acute leukemia. The patients with brain tumors had a significant delay from symptom onset to diagnosis. Only 38% of primary brain tumors were diagnosed within the first month after the onset of symptoms. In contrast, 84% of Wilms' tumors and 80% of cases of acute leukemia were diagnosed within one month of the onset of symptoms. Early detection of brain tumors is important as it may have a significant bearing on clinical outcome. (AJDC 1986;140:684-686) References 1. Patitch HS, Berg BO: Brain stem tumors of childhood and adolescence . AJDC 1970;119: 465-472. 2. Levine AS: Cancer in the Young . New York, Masson Publishers USA Inc, 1982, pp 695-697. 3. Tomida T: Statistical analysis of symptoms and signs in cerebellar astrocytoma and medulloblastoma , in Amador LV (ed): Brain Tumors in the Young . Springfield, Ill, Charles C Thomas Publisher, 1983, pp 514-525. 4. Villani R, Gaini SN, Tomei G: Follow-up study of brain stem tumors in children . Childs Brain 1975;1:126-135. 5. Gjerris F: Clinical aspects and long-term prognosis of infratentorial intracranial tumors in infancy and childhood . Acta Neurol Scand 1978;57:31-52.Crossref 6. Walker R, Lieberman AN, Pintor GA, et al: Transient neurologic disturbances, brain tumors, and normal computed tomography scans . Cancer 1983;52:1502-1506.Crossref 7. Weinblatt ME, Ortega JA, Miller JH, et al: The reliability of noninvasive diagnostic procedures in children with brain tumors . Am J Pediatr Hematol Oncol 1982;4:367-372.Crossref 8. Bailey CC: Brain tumors in childhood . Rec Results Cancer Res 1983;88:64-68. 9. Kopelson G, Lingood RM, Kleinman GM: Medulloblastoma: Identification of prognostic subgroups and implications for multimodal management . Cancer 1983;51:312-319.Crossref

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Jul 1, 1986

References