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Defective Epidermal Utilization and Storage of S35 in Psoriasis

Defective Epidermal Utilization and Storage of S35 in Psoriasis Abstract The problem of the etiology and physiochemical mechanism operative in the development of psoriasis has been a stimulant to the efforts of research workers in the field of dermatology. There has been no dearth of work on the part of dermatologists toward attempting to solve the mystery of this disease. In a 10-year period, from 1948-1957, Sulzberger and Baer1 and Baer and Whitten2 summarized 86 investigative studies on psoriasis. The great majority of this work has been directed toward methods of therapy and the study of chemical alterations. A summary of the literature of investigative work on psoriasis is to be found in Shelley and Arthur's review.3 Recently Flesch and Esoda4,5 reported their studies of the physical and chemical properties of the scales of psoriasis. They were able to find chemical differences unique enough to propose that these References 1. Sulzberger, M., and Baer, R., Editors: The Year Book of Dermatology and Syphilology (1949-1954) , Chicago, The Year Book Publishers, Inc., 1956. 2. Baer, R., and Whitten, V., Editors: The Year Book of Dermatology and Syphilology (1955-1958) , Chicago, The Year Book Publishers, Inc., 1958. 3. Shelley, W., and Arthur, R.: Biochemical and Physiological Clues to the Nature of Psoriasis , A. M. A. Arch. Dermat. 78:14 ( (July) ) 1958.Crossref 4. Flesch, P., and Esoda, E. C. J.: Defective Epidermal Protein Metabolism in Psoriasis , A. M. A. Arch. Dermat. 76:393 ( (Oct.) ) 1957.Crossref 5. Flesch, P., and Esoda, E. C. J.: Chemical Changes in Psoriatic Scales , Ann. New York Acad. Sc. 73:989 ( (Nov. 10) ) 1958.Crossref 6. Steiner, K.: Histochemical Observations on Parakeratosis , A. M. A. Arch. Dermat. 77:586 ( (May) ) 1958.Crossref 7. Lipnik, M., and Levy, S.: To be published. 8. Sandweiss, D., and Levy, S.: Gastrointestinal Absorption with Oleic Acid-I131 and L-Methionine-S35 in Patients with Ulcerative Colitis , Proc. Soc. Exper. Biol. & Med. 95:259 ( (June) ) 1957. 9. Levy, S.; Sandweiss, D.; Gagliardi, R., and Feigelson, H.: To be published. 10. Roe, D.: Application of Paper Electrophoresis to the Diagnosis of Psoriasis: A Study of Psoriatic Scale Extracts , Ann. New York Acad. Sc. 73:977 ( (Nov. 10) ) 1958. 11. Dziewiatkowski, D.: Isolation of Chondroitin Sulfate S35 from Articular Cartilage of Rats , J. Biol. Chem. 189:187 ( (Jan.) ) 1951. 12. Böstrom, H.: On the Metabolism of the Sulfate Group of Chondroitinsulfuric Acid , J. Biol. Chem. 196:477 ( (June) ) 1952. 13. Denko, C., and Priest, R.: Distribution of Radiosulfur S35 , J. Lab. & Clin. Med. 50:107 ( (July) ) 1957. 14. Böstrom, H., and Månsson, B.: On the Enzymatic Exchange of the Sulfate Group of Chondroitinsulfuric Acid in Slices of Cartilage , J. Biol. Chem. 196:483 ( (June) ) 1952. 15. Flesch, P., and Esoda, E. J., in Discussion on Flesch, P., and Esoda, E. C. J.4 16. Thorn, G. W., et al.: Medical Progress: The Clinical Usefulness of ACTH and Cortisone , New England J. Med. 242:783 ( (May 18) ) 1950. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology American Medical Association

Defective Epidermal Utilization and Storage of S35 in Psoriasis

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References (15)

Publisher
American Medical Association
Copyright
Copyright © 1959 American Medical Association. All Rights Reserved.
ISSN
0096-5359
DOI
10.1001/archderm.1959.01560190038005
Publisher site
See Article on Publisher Site

Abstract

Abstract The problem of the etiology and physiochemical mechanism operative in the development of psoriasis has been a stimulant to the efforts of research workers in the field of dermatology. There has been no dearth of work on the part of dermatologists toward attempting to solve the mystery of this disease. In a 10-year period, from 1948-1957, Sulzberger and Baer1 and Baer and Whitten2 summarized 86 investigative studies on psoriasis. The great majority of this work has been directed toward methods of therapy and the study of chemical alterations. A summary of the literature of investigative work on psoriasis is to be found in Shelley and Arthur's review.3 Recently Flesch and Esoda4,5 reported their studies of the physical and chemical properties of the scales of psoriasis. They were able to find chemical differences unique enough to propose that these References 1. Sulzberger, M., and Baer, R., Editors: The Year Book of Dermatology and Syphilology (1949-1954) , Chicago, The Year Book Publishers, Inc., 1956. 2. Baer, R., and Whitten, V., Editors: The Year Book of Dermatology and Syphilology (1955-1958) , Chicago, The Year Book Publishers, Inc., 1958. 3. Shelley, W., and Arthur, R.: Biochemical and Physiological Clues to the Nature of Psoriasis , A. M. A. Arch. Dermat. 78:14 ( (July) ) 1958.Crossref 4. Flesch, P., and Esoda, E. C. J.: Defective Epidermal Protein Metabolism in Psoriasis , A. M. A. Arch. Dermat. 76:393 ( (Oct.) ) 1957.Crossref 5. Flesch, P., and Esoda, E. C. J.: Chemical Changes in Psoriatic Scales , Ann. New York Acad. Sc. 73:989 ( (Nov. 10) ) 1958.Crossref 6. Steiner, K.: Histochemical Observations on Parakeratosis , A. M. A. Arch. Dermat. 77:586 ( (May) ) 1958.Crossref 7. Lipnik, M., and Levy, S.: To be published. 8. Sandweiss, D., and Levy, S.: Gastrointestinal Absorption with Oleic Acid-I131 and L-Methionine-S35 in Patients with Ulcerative Colitis , Proc. Soc. Exper. Biol. & Med. 95:259 ( (June) ) 1957. 9. Levy, S.; Sandweiss, D.; Gagliardi, R., and Feigelson, H.: To be published. 10. Roe, D.: Application of Paper Electrophoresis to the Diagnosis of Psoriasis: A Study of Psoriatic Scale Extracts , Ann. New York Acad. Sc. 73:977 ( (Nov. 10) ) 1958. 11. Dziewiatkowski, D.: Isolation of Chondroitin Sulfate S35 from Articular Cartilage of Rats , J. Biol. Chem. 189:187 ( (Jan.) ) 1951. 12. Böstrom, H.: On the Metabolism of the Sulfate Group of Chondroitinsulfuric Acid , J. Biol. Chem. 196:477 ( (June) ) 1952. 13. Denko, C., and Priest, R.: Distribution of Radiosulfur S35 , J. Lab. & Clin. Med. 50:107 ( (July) ) 1957. 14. Böstrom, H., and Månsson, B.: On the Enzymatic Exchange of the Sulfate Group of Chondroitinsulfuric Acid in Slices of Cartilage , J. Biol. Chem. 196:483 ( (June) ) 1952. 15. Flesch, P., and Esoda, E. J., in Discussion on Flesch, P., and Esoda, E. C. J.4 16. Thorn, G. W., et al.: Medical Progress: The Clinical Usefulness of ACTH and Cortisone , New England J. Med. 242:783 ( (May 18) ) 1950.

Journal

A.M.A. Archives of DermatologyAmerican Medical Association

Published: Jul 1, 1959

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