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D. Poll, J. Stern (1936)
UNTOWARD EFFECTS OF DIURESIS: WITH SPECIAL REFERENCE TO MERCURIAL DIURETICSJAMA Internal Medicine, 58
H. Greenwald, Seymour Jacobson (1937)
Sudden death due to mercurial diureticsThe Journal of Pediatrics, 11
I. Wolf, H. Bongiorno (1931)
SUDDEN DEATH WITH SALYRGAN.Canadian Medical Association journal, 25 1
Mercurial diuretics have been used freely for more than a dozen years. Poll and Stern1 have emphasized the dangers of extreme dehydration from overenthusiastic use of these drugs, and Greenwald and Jacobson2 have presented 2 cases and Wolf3 a third case of sudden death following an intravenous injection of a mercurial diuretic. I wish to present 2 further cases and to point out the striking similarities in all 5 cases. Greenwald and Jacobson's first case was that of a child aged 2 years with nephrosis who was given 0.5 cc. of neptal (a mercurial diuretic4) intramuscularly, followed by 1 cc. intramuscularly four days later. One week later 1 cc. of neptal given intravenously caused dyspnea, cyanosis, cardiac standstill and death within one minute of injection. Their second case was that of a child aged 3 years with nephrosis who received 0.5 cc. of neptal intravenously followed
JAMA – American Medical Association
Published: Sep 20, 1941
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