Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Cytologic Studies in Skin Cancer

Cytologic Studies in Skin Cancer Abstract For several years prior to 1943, Dr. Papanicolaou and his staff had been investigating a smear cytologic technique for the investigation of cancerous lesions of the vagina, cervix, and uterus. They found early that, because of the amount of blood and mucus in most smears from the vagina, the usual stains were inadequate as the technique stained all the material, so that finding the abnormal cells was difficult. They devised a stain which picked out the nuclei of aberrant cells and left most of the background unstained. All this material was published in a beautifully illustrated monograph entitled Diagnosis of Uterine Cancer by the Vagina Smear.1 Since that time, this technique has been very widely used, and there is a tremendous amount of literature on its application. Some time later, this technique was used in the investigation of pleural effusions, urine, gastric washings, smears from mouth and throat, bronchi, References 1. Papanicolaou, G. N., and Traut, H. F.: Diagnosis of Uterine Cancer by the Vaginal Smear , New York Commonwealth Fund, Oxford University Press, 1943. 2. Hitch, J. M.; Wilson, T. B., and Scoggin, A.: Evaluation of Rapid Method of Cytologic Diagnosis in Suspected Skin Cancer , South. M.J. 44: 407-414 ( (May) ) 1951.Crossref 3. Sandler, H. C.; Freund, H. R., and Stahl, S. S.: Exfoliative Cytology Applied to the Detection and Treatment of Head and Neck Cancer , Surgery 46:479-485 ( (Sept.) ) 1959. 4. Sandler, H. C., and Stahl, S. S.: Exfoliative Cytology as a Diagnostic Aid in the Detection of Oral Neoplasms , J. Oral Surg. 16:414-418 ( (Sept.) ) 1958. 5. Quero, R., and Maso, C.: Cytology in Paget's Disease of Nipple , J. Invest. Dermat. 31:307-311 ( (Dec.) ) 1958.Crossref 6. Hopp, E. S.: Cytologic Diagnosis and Prognosis in Carcinoma of the Mouth, Pharynx and Nasopharynx , Laryngoscope 68:1281-1287 (Aug., Pt. (2) ) 1958.Crossref 7. Moore, T. D.: A Simple Technique for the Diagnosis of Non-Lipid Histiocytoses (Letterer-Siwe Disease) , Pediatrics 19:438-445 ( (March) ) 1957. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Loading next page...
 
/lp/american-medical-association/cytologic-studies-in-skin-cancer-zIQZrKoabc
Publisher
American Medical Association
Copyright
Copyright © 1960 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1960.01580060148024
Publisher site
See Article on Publisher Site

Abstract

Abstract For several years prior to 1943, Dr. Papanicolaou and his staff had been investigating a smear cytologic technique for the investigation of cancerous lesions of the vagina, cervix, and uterus. They found early that, because of the amount of blood and mucus in most smears from the vagina, the usual stains were inadequate as the technique stained all the material, so that finding the abnormal cells was difficult. They devised a stain which picked out the nuclei of aberrant cells and left most of the background unstained. All this material was published in a beautifully illustrated monograph entitled Diagnosis of Uterine Cancer by the Vagina Smear.1 Since that time, this technique has been very widely used, and there is a tremendous amount of literature on its application. Some time later, this technique was used in the investigation of pleural effusions, urine, gastric washings, smears from mouth and throat, bronchi, References 1. Papanicolaou, G. N., and Traut, H. F.: Diagnosis of Uterine Cancer by the Vaginal Smear , New York Commonwealth Fund, Oxford University Press, 1943. 2. Hitch, J. M.; Wilson, T. B., and Scoggin, A.: Evaluation of Rapid Method of Cytologic Diagnosis in Suspected Skin Cancer , South. M.J. 44: 407-414 ( (May) ) 1951.Crossref 3. Sandler, H. C.; Freund, H. R., and Stahl, S. S.: Exfoliative Cytology Applied to the Detection and Treatment of Head and Neck Cancer , Surgery 46:479-485 ( (Sept.) ) 1959. 4. Sandler, H. C., and Stahl, S. S.: Exfoliative Cytology as a Diagnostic Aid in the Detection of Oral Neoplasms , J. Oral Surg. 16:414-418 ( (Sept.) ) 1958. 5. Quero, R., and Maso, C.: Cytology in Paget's Disease of Nipple , J. Invest. Dermat. 31:307-311 ( (Dec.) ) 1958.Crossref 6. Hopp, E. S.: Cytologic Diagnosis and Prognosis in Carcinoma of the Mouth, Pharynx and Nasopharynx , Laryngoscope 68:1281-1287 (Aug., Pt. (2) ) 1958.Crossref 7. Moore, T. D.: A Simple Technique for the Diagnosis of Non-Lipid Histiocytoses (Letterer-Siwe Disease) , Pediatrics 19:438-445 ( (March) ) 1957.

Journal

Archives of DermatologyAmerican Medical Association

Published: Dec 1, 1960

References