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Cutaneous Manifestations in Idiopathic Hypoparathyroidism

Cutaneous Manifestations in Idiopathic Hypoparathyroidism Abstract A 51-year-old man with idiopathic hypoparathyroidism that had been untreated for more than nine years developed erythematous lesions with erosion and lamellar scales resembling exfoliative dermatitis. Depilation of scalp and axillary hair, nail changes, and cataracts were also noted. These skin changes appeared almost simultaneously with severe reduction of the serum calcium level. Treatment with ergocalciferol and gluconate calcium greatly improved these dermal lesions as well as other hypocalcemic symptoms. Normalization of the serum calcium level followed. It is likely that exfoliative dermatitis-like lesions may occur as skin manifestations of idiopathic hypoparathyroidism, although such manifestations are extremely rare. References 1. Simpson JA: Dermatological changes in hypocalcemia . Br J Dermatol 66:1-16, 1954.Crossref 2. Freinkel RK, Freinkel N: Dermatologic manifestation of endocrine disorders , in Fitzpatrick TB, et al (eds): Dermatology in General Medicine . New York, McGraw-Hill, 1971, pp 1434-1459. 3. Lachmann A: Hypoparathyroidism in Denmark: A clinical study . Acta Med Scand , (suppl 121) , pp 1-269, 1941. 4. Harell-Steinberg A, et al: Observations on hypoparathyroidism: I. Exfoliative dermatitis as the presenting sign of hypoparathyroidism: A case report . J Clin Endocrinol Metab 17:1094-1098, 1957.Crossref 5. Dent CE, Garretts M: Skin changes in hypocalcaemia . Lancet 1:142-146, 1960.Crossref 6. Bronsky D, et al: Idiopathic hypoparathyroidism and pseudohypoparathyroidism: Case reports and review ot the literature . Medicine 37:317-352, 1958.Crossref 7. Sjöberg KH: Moniliasis-an internal disease? Three cases of idiopathic hypoparathyroidism with moniliasis, steatorrhea, primary amenorrhea and pernicious anemia . Acta Med Scand 179:157-166, 1966.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Cutaneous Manifestations in Idiopathic Hypoparathyroidism

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Publisher
American Medical Association
Copyright
Copyright © 1974 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1974.01630020054014
Publisher site
See Article on Publisher Site

Abstract

Abstract A 51-year-old man with idiopathic hypoparathyroidism that had been untreated for more than nine years developed erythematous lesions with erosion and lamellar scales resembling exfoliative dermatitis. Depilation of scalp and axillary hair, nail changes, and cataracts were also noted. These skin changes appeared almost simultaneously with severe reduction of the serum calcium level. Treatment with ergocalciferol and gluconate calcium greatly improved these dermal lesions as well as other hypocalcemic symptoms. Normalization of the serum calcium level followed. It is likely that exfoliative dermatitis-like lesions may occur as skin manifestations of idiopathic hypoparathyroidism, although such manifestations are extremely rare. References 1. Simpson JA: Dermatological changes in hypocalcemia . Br J Dermatol 66:1-16, 1954.Crossref 2. Freinkel RK, Freinkel N: Dermatologic manifestation of endocrine disorders , in Fitzpatrick TB, et al (eds): Dermatology in General Medicine . New York, McGraw-Hill, 1971, pp 1434-1459. 3. Lachmann A: Hypoparathyroidism in Denmark: A clinical study . Acta Med Scand , (suppl 121) , pp 1-269, 1941. 4. Harell-Steinberg A, et al: Observations on hypoparathyroidism: I. Exfoliative dermatitis as the presenting sign of hypoparathyroidism: A case report . J Clin Endocrinol Metab 17:1094-1098, 1957.Crossref 5. Dent CE, Garretts M: Skin changes in hypocalcaemia . Lancet 1:142-146, 1960.Crossref 6. Bronsky D, et al: Idiopathic hypoparathyroidism and pseudohypoparathyroidism: Case reports and review ot the literature . Medicine 37:317-352, 1958.Crossref 7. Sjöberg KH: Moniliasis-an internal disease? Three cases of idiopathic hypoparathyroidism with moniliasis, steatorrhea, primary amenorrhea and pernicious anemia . Acta Med Scand 179:157-166, 1966.Crossref

Journal

Archives of Dermatology – American Medical Association

Published: Feb 1, 1974

References

  • Dermatological changes in hypocalcemia
    Simpson JA
  • Dermatology in General Medicine
    Freinkel RK, Freinkel N
  • Hypoparathyroidism in Denmark: A clinical study
    Lachmann A
  • Observations on hypoparathyroidism: I. Exfoliative dermatitis as the presenting sign of hypoparathyroidism: A case report
    Harell-Steinberg A, et al
  • Skin changes in hypocalcaemia
    Dent CE, Garretts M
  • Idiopathic hypoparathyroidism and pseudohypoparathyroidism: Case reports and review ot the literature
    Bronsky D, et al
  • Moniliasis-an internal disease? Three cases of idiopathic hypoparathyroidism with moniliasis, steatorrhea, primary amenorrhea and pernicious anemia
    Sjöberg KH