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J. Cohn, D. Carroll, R. Riley (1954)
Respiratory acidosis in patients with emphysema.The American journal of medicine, 17 4
W. Miller (1954)
A physiologic evaluation of the effects of diaphragmatic breathing training in patients with chronic pulmonary emphysema.The American journal of medicine, 17 4
R. Monroe (1951)
Diseases in Old Age: A Clinical and Pathological Study of 7941 Individuals Over 61 Years of Age
R. T. H. Laennec (1823)
A Treatise on the Diseases of the Chest, in Which They Are Described According to Their Anatomical Characters and Their Diagnosis Established on a New Principle by Means of Acoustick Instruments
A. Hurst, M. Levine (1955)
Radioactive iodine in treatment of pulmonary emphysema.Rocky Mountain medical journal, 52 2, Part 1
R. Miller, W. Fowler, H. Helmholz (1955)
The treatment of pulmonary emphysema and of diffuse pulmonary fibrosis with nebulized bronchodilators and intermittent positive pressure breathing.Diseases of the chest, 28 3
B. A. Bercu (1954)
Radioactive Iodine for Chronic Lung DiseaseClin. Res. Proc., 2
M. Becklake, And GOLDMAN, M. Mggregor (1954)
The Effects of Pneumoperitoneum on Lung Function in Pulmonary EmphysemaThorax, 9
O. Abbott, W. Hopkins, W. FLEIT, J. Robinson (1953)
A New Approach to Pulmonary EmphysemaThorax, 8
W. B. Kountz (1934)
EmphysemaMedicine, 13
R. Christie (1944)
Emphysema of the Lungs—I*British Medical Journal, 1
M. Carter, E. Gaensler, A. Kyllonen (1950)
Pneumoperitoneum in the treatment of pulmonary emphysema.The New England journal of medicine, 243 15
RÉJANE Harvey, M. Ferrer, André Cournand (1953)
The Treatment of Chronic Cor PulmonaleCirculation, 7
M. Segal, M. Dulfano (1953)
Chronic pulmonary emphysema : physiopathology and treatment
Walker Je (1949)
Emphysema of the lungs.Treatment services bulletin. Canada. Department of Veterans' Affairs, 4
A. Barach, G. Beck (1954)
The ventilatory effects of the head-down position in pulmonary emphysema.The American journal of medicine, 16 1
H. L. Motley (1952)
Treatment of Chronic Pulmonary Disease with Intermittent Positive Pressure Breathing: I. Evaluation by Objective Physiological MeasurementsA. M. A. Arch. Indust. Hyg., 5
J. Nadell (1953)
The Effects of Carbonic Anhydrase Inhibitor "6063" on Electrolytes and Acid-Base Balance in 2 Normal Subjects and 2 Patients With Respiratory AcidosisJ. Clin. Invest., 32
J. H. Comroe (1950)
Methods in Medical Research
Motley Hl, Tomashefski Jf (1952)
Treatment of chronic pulmonary disease with intermittent positive pressure breathing. 1. Evaluation by objective physiological measurements.A.M.A. archives of industrial hygiene and occupational medicine, 5
D. Fry, R. Ebert, W. Stead, C. Brown (1954)
The mechanics of pulmonary ventilation in normal subjects and in patients with emphysema.The American journal of medicine, 16 1
Abstract Since Laennec 1 described the clinical and pathological features of pulmonary emphysema, more than a century ago, much has been learned about its pathologic physiology and its progressive clinical course, with cardiac and metabolic complications. However, the initial inciting factors and early pathogenesis still are poorly understood. Because of this hiatus in knowledge, the clinical recognition of emphysema in its early stages is frequently difficult and the results of treatment, once the diagnosis is made, often are disappointing. DEFINITION Numerous types of emphysema have been described, as have many concepts concerning their relative clinical importance. Thus, an attempt at definition appears advisable before the clinically diagnostic criteria are considered. Pulmonary emphysema is characterized pathologically by large alveolar spaces with attenuated septa, many of which are fragmented; as a result, larger air spaces (blebs or bullae) are formed, thus altering the mechanical (viscoelastic) properties and ventilation of the lungs, as well References 1. Comroe,5 Vol. 2, pp. 76-244. 2. Comroe,5 Vol. 2, pp. 188-197. 3. References 11 and 12. 4. References 13 and 14. 5. Laennec, R. T. H.: A Treatise on the Diseases of the Chest, in Which They Are Described According to Their Anatomical Characters and Their Diagnosis Established on a New Principle by Means of Acoustick Instruments , translated by John Forbes, Philadelphia, James Webster, 1823, p. 87. 6. Monroe, R. T.: Diseases in Old Age: A Clinical and Pathologic Study of 7941 Individuals Over 61 Years of Age , Cambridge, Harvard University Press, 1951. 7. Christie, R. V.: Emphysema of the Lungs , Brit. M. J. 1:105-108 ( (Jan. 15) )Crossref 8. 143-146 (Jan. 29) 1944. 9. Fry, D. L.; Ebert, R. V.; Stead, W. W., and Brown, C. C.: The Mechanics of Pulmonary Ventilation in Normal Subjects and in Patients with Emphysema , Am. J. Med. 16:80-97 ( (Jan.) ) 1954.Crossref 10. Comroe, J. H., Jr.: Methods in Medical Research , Chicago, The Year Book Publishers, Inc., 1950. 11. Motley, H. L., and Tomashefski, J. F.: Treatment of Chronic Pulmonary Disease with Intermittent Positive Pressure Breathing: I. Evaluation by Objective Physiological Measurements , A. M. A. Arch. Indust. Hyg. 5:1-9 ( (Jan.) ) 1952. 12. Miller, R. D.; Fowler, W. S., and Helmholz, H. F., Jr.: The Treatment of Pulmonary Emphysema and of Diffuse Pulmonary Fibrosis with Nebulized Bronchodilators and Intermittent Positive Pressure Breathing , Dis. Chest , to be published. 13. Barach, A. L., and Beck, G. J.: The Ventilatory Effects of the Head-Down Position in Pulmonary Emphysema , Am. J. Med. 16:55-60 ( (Jan.) ) 1954.Crossref 14. Miller, W. F.: A Physiologic Evaluation of the Effects of Diaphragmatic Breathing Training in Patients with Chronic Pulmonary Emphysema , Am. J. Med. 17:471-477 ( (Oct.) ) 1954.Crossref 15. Kountz, W. B., and Alexander, H. L.: Emphysema , Medicine 13:251-316 ( (Sept.) ) 1934.Crossref 16. Carter, M. G.; Gaensler, E. A., and Kyllonen, A.: Pneumoperitoneum in the Treatment of Pulmonary Emphysema , New England J. Med. 243: 549-558 ( (Oct. 12) ) 1950.Crossref 17. Becklake, M. R.; Goldman, H. I., and McGregor, M.: The Effects of Pneumoperitoneum on Lung Function in Pulmonary Emphysema , Thorax 9:222-225 ( (Sept.) ) 1954.Crossref 18. Hurst, A., and Levine, M. H.: Radioactive Iodine in Treatment of Pulmonary Emphysema , Rocky Mountain M. J. 52:129-131 ( (Feb.) ) 1955. 19. Bercu, B. A., and Mandell, H. N.: Radioactive Iodine for Chronic Lung Disease , Clin. Res. Proc. 2:107 ( (April) ) 1954. 20. Nadell, J., and Kalinsky, H.: The Effects of Carbonic Anhydrase Inhibitor "6063" on Electrolytes and Acid-Base Balance in 2 Normal Subjects and 2 Patients With Respiratory Acidosis , J. Clin. Invest. 32:622-629 ( (July) ) 1953.Crossref 21. Abbot, O. A.; Hopkins, W. A.; Van Fleit, W. E., and Robinson, J. S.: A New Approach to Pulmonary Emphysema , Thorax 8:116-132 ( (June) ) 1953.Crossref 22. Cohn, J. E.; Carroll, D. G., and Riley, R. L.: Respiratory Acidosis in Patients with Emphysema , Am. J. Med. 17:447-463 ( (Oct.) ) 1954.Crossref 23. Segal, M. S., and Dulfano, M. J.: Chronic Pulmonary Emphysema: Physiopathology and Treatment , New York, Grune & Stratton, Inc., 1953. 24. Harvey, R. M.; Ferrer, M. I., and Cournand, A.: The Treatment of Chronic Cor Pulmonale , Circulation 7:932-940 ( (June) ) 1953.Crossref
A.M.A. Archives of Internal Medicine – American Medical Association
Published: Sep 1, 1955
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